L-Prolyl-L-leucylglycinamide
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L-Prolyl-L-leucylglycinamide
structure -
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CAS No:
2002-44-0
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Formula:
C13H24N4O3
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Chemical Name:
L-Prolyl-L-leucylglycinamide
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Synonyms:
Glycinamide,L-prolyl-L-leucyl-;2-Pyrrolidinecarboxamide,N-[1-[(carbamoylmethyl)carbamoyl]-3-methylbutyl]-;L-Prolyl-L-leucylglycinamide;L-Proline-L-leucine-glycine-amide;Pro-Leu-Gly-NH2;H-Pro-Leu-Gly-NH2;Melanocyte-stimulating hormone release-inhibiting factor I (ox);L-Prolyl-L-leucylglycylamide;L-Prolyl-L-leucyl-glycine amide;MSH-release inhibiting factor I;Melanocyte-stimulating hormone release-inhibiting factor I;Prolylleucylglycine amide;Prolyleucyl-glycinamide;Melanostatin I (ox);MIF-I;MIF-1;Oxytocin C-terminal tripeptide;7-9-Oxytocin;26: PN: US6093797 PAGE: 15 claimed protein;27: PN: US6093797 PAGE: 15 claimed protein;2: PN: WO2009039992 PAGE: 107 claimed protein;Melanocyte-stimulating hormone release-inhibiting factor 1;15569-83-2
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CAS No:
Description
Solid
Solid
Melanostatin is an oligopeptide.|A hypothalamic tripeptide, enzymatic degradation product of OXYTOCIN, that inhibits the release of MELANOCYTE-STIMULATING HORMONES.
Characteristics
113
-1.4
Solid
1.147g/cm3
122-123 °C @ Solvent: Water
626.2°C at 760 mmHg
332.5ºC
1.51
Soluble in water.
-15ºC
1.34E-15mmHg at 25°C
Drug Information
Chemical substances having a specific regulatory effect on the activity of a certain organ or organs. The term was originally applied to substances secreted by various ENDOCRINE GLANDS and transported in the bloodstream to the target organs. It is sometimes extended to include those substances that are not produced by the endocrine glands but that have similar effects. (See all compounds classified as Hormones.)
H-Pro-Leu-Gly-NH2
Computed Properties
Molecular Weight:284.35
XLogP3:-1.4
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:284.18484064
Monoisotopic Mass:284.18484064
Topological Polar Surface Area:113
Heavy Atom Count:20
Complexity:371
Defined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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