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3-Oxocholic acid

3-Oxocholic acid structure

3-Oxocholic acid 

structure
  • CAS No:

    2304-89-4

  • Formula:

    C24H38O5

  • Chemical Name:

    3-Oxocholic acid

  • Synonyms:

    Cholan-24-oic acid,7,12-dihydroxy-3-oxo-,(5β,7α,12α)-;5β-Cholan-24-oic acid,7α,12α-dihydroxy-3-oxo-;5β-Cholanic acid,7α,12α-dihydroxy-3-oxo-;(5β,7α,12α)-7,12-Dihydroxy-3-oxocholan-24-oic acid;7α,12α-Dihydroxy-3-keto-5β-cholanic acid;7α,12α-Dihydroxy-3-oxocholanic acid;7α,12α-Dihydroxy-3-oxo-5β-cholan-24-oic acid;3-Oxo-7α,12α-dihydroxycholan-24-oic acid;3-Oxo-7α,12α-dihydroxy-5β-cholanic acid;7α,12α-Dihydroxy-3-oxo-5β-cholanic acid;3-Oxocholic acid;3-keto-7α,12α-Dihydroxy-5β-cholanic acid;3-Oxo-7α,12α-dihydroxy-5β-cholanoic acid;7α,12α-Dihydroxy-3-oxo-5β-cholanoic acid;3-Ketocholic acid;3-Dehydrocholic acid;3-Oxo-7a,12a-dihydroxy-5b-cholanic acid;901129-84-8

Description

3-Oxocholic acid is an oxo-bile acid metabolite and also a major degradation product from cholic by C. perfringens in the intestine. 3-Oxocholic acid is steroid acid found predominantly in bile of mammals[1][2][3].

3-Oxocholic acid Basic Attributes

406.6

406.56

Characteristics

94.83000

3.65690

1.180±0.06 g/cm3(Predicted)

185 °C

3-Oxocholic acid Use and Manufacturing

3-Oxo-7α,12α-hydroxy-5β-cholanoic Acid is a keto bile acid derivative.

Computed Properties

Molecular Weight:406.6
XLogP3:3.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:406.27192431
Monoisotopic Mass:406.27192431
Topological Polar Surface Area:94.8
Heavy Atom Count:29
Complexity:676
Defined Atom Stereocenter Count:10
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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