Cypromid

230.09100

230.09

1243H370PQ

DTXSID3041827

2924299035

32.59000

3.99140

1.477g/cm3

127-129 °C

402.7ºC at 760mmHg

197.3ºC

1.658

In water, > 0.01 g/100mL

3.7X10-6 mm Hg at 25 deg C /Estimated/

Henry's Law constant: 2.6X10-3 atm cu m/mole at 25 °C /Estimated/

Hydroxyl radical reaction rate constant: 2.8X10-12 cu cm/mole-sec at 25 °C /Estimated/

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.

SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

Mildly irritating.

LD50 Mice percutaneous greater than 4500 mg/kg|LD50 Mice (male) oral 1330 mg/kg|LD50 Mice (female) oral 1580 mg/kg|LD50 Rats (male) oral 2333 mg/kg|For more Non-Human Toxicity Values (Complete) data for CYPROMID (8 total), please visit the HSDB record page.

/AQUATIC SPECIES/ Toxicity to Bufo Bufo japonicus was determined. The stage of development had little effect on toxicity.

Cypromid's former production and use as a herbicide(1) resulted in its direct release to the environment(SRC).

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 2,900(SRC), determined from a log Kow of 3.83(2) and a regression-derived equation(3), indicates that cypromid is expected to have slight mobility in soil(SRC). Volatilization of cypromid from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 2.6X10-9 atm-cu m/mole(SRC), using a fragment constant estimation method(4). Cypromid is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 3.7X10-6 mm Hg(SRC), determined from a fragment constant method(5). Biodegradation data were not available(SRC, 2005).|AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 2,900(SRC), determined from a log Kow of 3.83(2) and a regression-derived equation(3), indicates that cypromid is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is not expected(3) based upon an estimated Henry's Law constant of 2.6X10-9 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4). According to a classification scheme(5), an estimated BCF of 480(SRC), from its log Kow(2) and a regression-derived equation(6), suggests the potential for bioconcentration in aquatic organisms is high(SRC). Hydrolysis is not expected to be an important environmental fate process since cypromid lacks functional groups that hydrolyze under environmental conditions. Biodegradation data were not available(SRC, 2005).|ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), cypromid, which has an estimated vapor pressure of 3.7X10-6 mm Hg at 25 °C(SRC), determined from a fragment constant method(2), will exist in both the vapor and particulate phases in the ambient atmosphere. Vapor-phase cypromid is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 5.8(SRC), calculated from its rate constant of 2.8X10-12 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3). Particulate-phase cypromid may be removed from the air by wet and dry deposition(SRC). Cypromid does not contain chromophores that absorb at wavelengths >290 nm and therefore would not be expected to be susceptible to direct photolysis by sunlight(SRC).

The rate constant for the vapor-phase reaction of cypromid with photochemically-produced hydroxyl radicals has been estimated as 2.8 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1). This corresponds to an atmospheric half-life of about 5.8 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1). Hydrolysis is not expected to be an important environmental fate process since cypromid lacks functional groups that hydrolyze under environmental conditions. Cypromid does not absorb light at wavelengths >290 nm and would not be expected to be susceptible to direct photolysis by sunlight(SRC).

An estimated BCF of 480 was calculated for cypromid(SRC), using a log Kow of 3.83(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is high(SRC).

The Koc of cypromid is estimated as 2,900(SRC), using a log Kow of 3.83(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that cypromid is expected to have slight mobility in soil.

The Henry's Law constant for cypromid is estimated as 2.6X10-9 atm-cu m/mole(SRC) using a fragment constant estimation method(1). This Henry's Law constant indicates that cypromid is expected to be essentially nonvolatile from water surfaces(2). Cypromid's Henry's Law constant indicates that volatilization from moist soil surfaces will not occur(SRC). Cypromid is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 3.7X10-6 mm Hg(SRC), determined from a fragment constant method(3).

Occupational exposure and general population exposure should be low or non-existent since cypromid is no longer produced or used. In the past, cypromid was applied directly to the plants as an herbicide and exposure to this compound was primarily by inhalation and dermal contact. (SRC)

Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if needed. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Cover skin burns with dry sterile dressings after decontamination ... . /Poison A and B/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in respiratory arrest. Positive pressure ventilation techniques with a bag valve mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start an IV with D5W /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Poison A and B/

Production discontinued by Gulf Oil Chemicals Co.|Formerly in experimental use for post-emergence control of seeding weeds & Grass in corn & onions.

A CHROMATOGRAPHIC METHOD FOR DETECTION & IDENTIFICATION OF CARBAMATE, ANILIDE, & UREA PESTICIDES BY FORMATION OF PI-COMPLEXES WITH ELECTRON DONOR-ACCEPTOR REAGENTS DESCRIBED. DETECTION LIMIT AFTER TLC WAS 0.5-5.0 MUG, DEPENDING ON THE COMPLEX STRENGTH.