1H-Imidazole-5-acetic acid, hydrochloride (1:1)
-
1H-Imidazole-5-acetic acid, hydrochloride (1:1)
structure -
-
CAS No:
3251-69-2
-
Formula:
C5H6N2O2.ClH
-
Chemical Name:
1H-Imidazole-5-acetic acid, hydrochloride (1:1)
-
Synonyms:
1H-Imidazole-5-acetic acid,hydrochloride (1:1);Imidazole-4-acetic acid,monohydrochloride;Imidazoleacetic acid hydrochloride;1H-Imidazole-4-acetic acid,monohydrochloride;Imidazole-4-acetic acid hydrochloride;1H-Imidazole-4-acetic acid,hydrochloride;Imidazol-4-acetic acid hydrochloride;1H-Imidazole-5-acetic acid hydrochloride;(1H-Imidazol-4-yl)acetic acid hydrochloride;(1H-Imidazol-5-yl)acetic acid hydrochloride;2-(1H-Imidazol-5-yl)acetic acid hydrochloride;2-(1H-Imidazol-4-yl)acetic acid hydrochloride;27146-04-9
-
Categories:
Active Pharmaceutical Ingredients > Circulatory System Drugs
-
CAS No:
1H-Imidazole-5-acetic acid, hydrochloride (1:1) Basic Attributes
162.57
162.019608
3701591
221-840-6
ET7A74ROAO
DTXSID00186237
2933290090
Characteristics
66
0.83880
White to light yellow Crystalline Powder
1.426g/cm3
127 °C
447.3ºC at 760mmHg
224.3ºC
soluble in water.water: soluble 100mg/mL, clear, faintly yellow
2-8°C
124 Ų [M+H]+
Safety Information
IRRITANT
NONH for all modes of transport
3
36/37/38-22
22-24/25-36/37/39-27-26-37/39
Xn,Xi
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
H315
|Warning|H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 2 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
1H-Imidazole-5-acetic acid, hydrochloride (1:1) Use and Manufacturing
4-lmidazoleacetic acid hydrochloride (5.93 g, 36.47 mmol) in methanol (125 mL) was saturated with HCI gas and stirred at room temperature for 5.5 h, then concentrated to give a quantitative yield of 4-imidazoleacetic acid methyl ester hydrochloride as a white solid which had NMR (MeOH- d4) delta 8.87 (d, J = 1.2 Hz, 1H), 7.46 (s, 1 H), 3.89 (s, 2H) 3.72 Step A: methyl 2-(lH-imidazol-4-yl)acetate hydrochloride To a solution of 2-(lH-imidazol-4-yl)acetic acid hydrochloride (200mg, 1.23 mmol) in methanol (5ml ) was added SOCl2 (145mg, 1.23 mmol). The reaction mixture was concentrated after two hours to give the desired product. LC-MS : m/z (M+H)= 141.1Step A: methyl 2-(lH-imidazol-4-yl)acetate hydrochloride To a solution of 2-(lH-imidazol-4-yl)acetic acid hydrochloride (200mg, 1.23 mmol) in methanol (5ml ) was added SOCl2 (145mg, 1.23 mmol). The reaction mixture was concentrated after two hours to give the desired product. LC-MS : m/z (M+H)= 141.1
Computed Properties
Molecular Weight:162.57
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:162.0196052
Monoisotopic Mass:162.0196052
Topological Polar Surface Area:66
Heavy Atom Count:10
Complexity:116
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
Recommended Suppliers of 1H-Imidazole-5-acetic acid, hydrochloride (1:1)
-
![China]()
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives -
![China]()
CN
5 YRS
Business licensedTrader Supplier of PVC resin,pvc paste resin,melamineInquiryCAS No.: 3251-69-2Grade: Industrial GradeContent: 99% -
![China]()
CN
5 YRS
Business licensedTrader Supplier of Material intermediates,Pharmaceutical intermediates,Functional intermediatesInquiryCAS No.: 3251-69-2Grade: Industrial GradeContent: 99% -
![China]()
CN
2 YRS
Business licensed Certified factoryManufactory Supplier of 4-(Pentafluorothio)aniline,Pentafluoro,Pentafluorothio,Pentafluorosulfur,[4-(bromomethyl)phenyl]-pentafluoro-lambda6-sulfane,[4-(pentafluoro-sulfanyl)phenyl]acetic acidInquiryCAS No.: 3251-69-2Grade: Industrial GradeContent: 95%
Learn More Other Chemicals
-
Cyclopropanecarboxylic acid, 1-amino-2-ethenyl-, ethyl ester, hydrochloride (9CI)
681807-60-3
-
Carbonic acid, 4-[[(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino]-3-[(ethoxycarbonyl)thio]-3-penten-1-yl ethyl ester, hydrochloride (1:1)
616-96-6
-
Carbamic acid, N-[2-(heptyloxy)phenyl]-, 2-(1-piperidinyl)ethyl ester, hydrochloride (1:1)
55792-21-7
-
Benzeneacetic acid, α-imino-3,4-dimethoxy-, methyl ester, hydrochloride (1:1) Formula
67828-59-5
-
Butanedioic acid, 1-[2-(2-chloro-5-methylphenoxy)-1-[[(1,1-dimethylethyl)amino]methyl]ethyl] 4-[2-[(1-oxohexadecyl)oxy]-1-[[(1-oxohexadecyl)oxy]methyl]ethyl] ester, hydrochloride (1:1) Formula
99026-79-6
-
Carbamimidothioic acid, C,C′-2,3-quinoxalinediyl ester, hydrochloride (1:2) Formula
63549-18-8
-
Benzeneacetic acid, 2,4-dihydroxy-α-imino-, ethyl ester, hydrochloride (1:1) Structure
35092-73-0
-
21H,23H-Porphine-2,18-dipropanoic acid, 3,7,12,17-tetramethyl-8,13-disulfo-, hydrochloride (1:2) Structure
623946-74-7
-
What is 21H,23H-Porphine-2,7,12,18-tetrapropanoic acid, 3,8,13,17-tetramethyl-, hydrochloride (1:2)
68938-73-8
-
What is Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-, [6-(hydroxymethyl)-2-pyridinyl]methyl ester, hydrochloride (1:1)
21550-30-1
1H-Imidazole-5-acetic acid, hydrochloride (1:1)
SDSRequest for Quotation