Homosalate

Liquid.A homolog of menthyl salicylate.Viscous or light yellow to slightly tan liquid or oil.

3,3,5-trimethylcyclohexylsalicylate appears as viscous or light yellow to slightly tan liquid or oil. (NTP, 1992)|Liquid

3,3,5-trimethylcyclohexylsalicylate appears as viscous or light yellow to slightly tan liquid or oil. (NTP, 1992)|2-hydroxybenzoic acid (3,3,5-trimethylcyclohexyl) ester is a benzoate ester and a member of phenols. It derives from a salicylic acid.|Homosalate is an organic compound that belongs to salicylates. It is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol. Salicylates prevent direct skin exposure to the sun’s harmful rays by absorbing ultraviolet (UV) light. Homosalate specifically absorbs short-wave UVB rays, which are associated with DNA damage and increased risk of skin cancer. It is a common ingredient in many commercially available sunscreens. There are no reported adverse effects from homosalate.

250 ml three-necked flask, 10.0 g of methyl salicylate, 23.3 g of 3, 3, 5-trimethylcyclohexanol, 0.50 g of potassium carbonate, Ammonium bromide 0.1g, heated to 180 reaction 13h, gas chromatography detection reaction system methyl salicylate conversion was 97.2percent.To vacuum distillation unit, the former fraction recovery to be applied, ColorlessMing of the Hu Moluo13.98 g, Yield 81.1percent, GCPurity greater than 99percent.250 ml three-necked flask, 10.0 g of methyl salicylate, 23.3 g of 3, 3, 5-trimethylcyclohexanol, 0.50 g of potassium carbonate, Ammonium bromide 0.1g, heated to 180 reaction 13h, gas chromatography detection reaction system methyl salicylate conversion was 97.2%.To vacuum distillation unit, the former fraction recovery to be applied, ColorlessMing of the Hu Moluo13.98 g, Yield 81.1%, GCPurity greater than 99%.50 g of 3, 3, 5-trimethylcyclohexyl ester (Salicylate derivatives, such as: 2-ethylhexyl salicylate (e.g. Eusolex OS), 4-isopropylbenzyl salicylate (e.g. Megasol), or 3, 3, 5-trimethylcyclohexyl salicylate (e.g. Salicylate derivatives, such as 2-ethylhexyl salicylate (e.g. Eusolex OS), 4-isopropylbenzyl salicylate (e.g. Megasol) or 3, 3, 5-trimethylcyclohexyl salicylate (e.g. salicylate derivatives, such as 2-ethylhexyl salicylate (eg, Eusolex OS), 4-isopropylbenzyl salicylate (eg, Megasol) or 3, 3, 5-trimethylcyclohexyl salicylate (eg, salicylate derivatives, such as 2-ethylhexyl salicylate (e.g. Eusolex OS), 4-isopropylbenzyl salicylate (e.g. Megasol), or 3, 3, 5-trimethyl cyclohexyl salicylate (e.g. salicylate derivatives, such as 2-ethylhexyl salicylate (e.g. Eusolex OS), 4-isopropylbenzyl salicylate (e.g. Megasol) or 3, 3, 5-trimethylcyclohexyl salicylate (e.g. the following salicylates: Potassium or triethanolamine salicylate Amyl salicylate Menthyl salicylate Homomenthyl salicylate 2-Ethylhexyl salicylate Phenyl salicylate Benzyl salicylate para-Isopropanolphenyl salicylate Isodecyl salicylate Homomenthyl N-acetylanthranilateAt least one of the following compounds is preferably employed as an agent absorbing the UV rays: 2-ethylhexyl p-(dimethylamino)benzoate (Escalot 507) 2-ethylhexyl p-methoxycinnamate (Parsol MCX) 3-benzylidene-d, l-camphor 3-(4'-methylbenzylidene)-d, l-camphor (Eusolex 6300) amyl 4-(dimethylamino)benzoate (Escalol 506) homomenthyl salicylate (Filtrasol A) 2-hydroxy-4-methoxybenzophenone (Uvinul M 40 - SpectraSorb UV 9) N-(2-ethylhexyl)-4-(3'-methylidenecamphor)benzene sulphonamidesalicylate derivatives, such as 2-ethylhexyl salicylate (for example Eusolex OS), 4-isopropylbenzyl salicylate (for example Megasol) or 3, 3, 5-trimethylcyclohexyl salicylate (for example PEG-25 PABA, The preferred organic screening agents are selected from among: Ethylhexyl methoxycinnamate, Ethylhexyl salicylate, The preferential additional organic photoprotective agents are chosen from: Ethylhexyl methoxycinnamate, The preferred additional organic photoprotective agents are selected from among: Ethylhexyl Methoxycinnamate; The preferred organic screening agents are selected from: Ethylhexyl Methoxycinnamate, Ethylhexyl Salicylate, The preferred additional organic screening agents are selected from among: Ethylhexyl methoxycinnamate, The preferred additional organic photoprotective agents are selected from among: Ethylhexyl methoxycinnamate, The preferred organic photoprotective agents are selected from among: Ethylhexyl methoxycinnamate, Ethylhexyl salicylate, In the context of the invention and in one particular embodiment, the following hydrophobic sunscreen agents (B) are employed in the kit according to the invention: derivative of dioctylbutylamidotriazone chemically bonded thereto plus ethylhexyl salicylate dimethicodiethyl benzalmalonate homosalatederivative of hexyl 2-(4'-(diethylamino)-2'-hydroxybenzoyl)benzoate chemically bonded thereto plus ethylhexyl salicylate dimethicodiethyl benzalmalonate homosalatederivative of tris(2-ethylhexyl) 4, 4', 4'-(1, 3, 5-triazine-2, 4, 6-triyltriimino)trisbenzoate chemically bonded thereto plus ethylhexyl salicylate dimethicodiethyl benzalmalonate homosalate4, 4'-diarylbutadiene derivative chemically bonded thereto plus ethylhexyl salicylate dimethicodiethyl benzalmalonate homosalateThe preferred organic screening agents are selected from: Ethylhexyl Methoxycinnamate, Ethylhexyl Salicylate, The preferred additional organic screening agents are selected from among: Butyl methoxydibenzoylmethane, Ethylhexyl methoxycinnamate, Ethylhexyl salicylate, The preferred organic screening agents are chosen from: Butylmethoxydibenzoylmethane, Ethylhexyl Methoxycinnamate, Ethylhexyl Salicylate, The preferred organic photoprotective agents are chosen from: Ethylhexyl methoxycinnamate, Ethylhexyl salicylate, The preferred ones are The preferred organic screens are chosen from: ethylhexyl methoxycinnamate, ethylhexyl salicylate, homosalate, butylmethoxydibenzoylmethane, phenylbenzimidazolesulphonic acid, Those preferred are: The preferred organic screening agents are chosen from: Butyl methoxydibenzoylmethane, Ethylhexyl methoxycinnamate, Ethylhexyl salicylate, The preferred organic screening agents are chosen from: Butyl methoxydibenzoylmethane, Ethylhexyl methoxycinnamate, Ethylhexyl salicylate, Benzoxazole Derivatives: 2, 4-Bis[4-[5-(1, 1-dimethylpropyl)benzoxazol-2-yl]phenylimino]-6-[(2-ethylhexyl)imino]-1, 3, 5-triazine, sold under the name of Uvasorb K2A by Sigma 3V, and mixtures thereof. The preferential organic screening agents are chosen from: Ethylhexyl Methoxycinnamate, Ethylhexyl Salicylate, salicylate derivatives, such as 2-ethylhexyl salicylate (for example Neo Heliopan OS, sold by Symrise), 4-isopropylbenzyl salicylate (for example Megasol), 3, 3, 5-trimethylcyclohexyl salicylate (A preparation according to claims 1 or 2, wherein the preparation comprises at least an additional UV absorbing substance selected from the group consisting of: - 3-(4'-trimethylammonium)benzylidenebornan-2-one methyl sulphate- homomenthyl salicylate- 2-ethylhexyl 2-cyano-3, 3-diphenylacrylate- N-[(2 and 4)-[2-(oxoborn-3-ylidene)methyl]benzyl]acrylamide polymer- 2-ethylhexyl p-methoxycinnamate

UV screen, analgesic

Odor agents

Personal care products

100,000 - 500,000 lb

Molecular Weight:262.34
XLogP3:5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:262.15689456
Monoisotopic Mass:262.15689456
Topological Polar Surface Area:46.5
Heavy Atom Count:19
Complexity:324
Undefined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes