Cobalt diacetate

118.98500

118.95400

200-755-8

3XC4P44U7E

DTXSID6026373

Light pink crystals|Pink crystals

37.30000

0.09090

Cobalt acetate is a red-violet crystalline solid. Vinegar-like odor. (USCG, 1999)

1.13 g/cm³

298ºC (dec.)

117.1ºC at 760 mmHg

40ºC

Mol wt: 249.08; Index of refraction: 1.542 /Tetrahydrate/

Soluble in waterSoluble in water, alcohol, dilute acids and pentyl acetate(tetrahydrate).

Separated from strong oxidants. Well closed. /Tetrahydrate ("The recommendations on this Card also apply to Cobalt (II) acetate anhydrous (CAS 71-48-7).")/

Reacts with strong oxidants causing fire and explosion hazard. /Tetrahydrate ("The recommendations on this Card also apply to Cobalt (II) acetate anhydrous (CAS 71-48-7).")/

Vinegar-like odor

Reddish-violet, deliquescent crystals /Cobalt(2+) acetate tetrahydrate/|Vinegar like odor /Tetrahydrate/|Red, needle like crystals /Tetrahydrate/|Hygroscopic|Refractive index: 1.542 /Cobalt (2+) acetate tetrahydrate/

Water soluble. Deliquescent

Salts, Basic

Salts, basic, such as COBALT ACETATE, are generally soluble in water. The resulting solutions contain moderate concentrations of hydroxide ions and have pH's greater than 7.0. They react as bases to neutralize acids. These neutralizations generate heat, but less or far less than is generated by neutralization of the bases in reactivity group 10 (Bases) and the neutralization of amines. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.

UN 3077 9 / PGIII

2

R22; R36/37/38; R40; R43; R53

S22-S26-S36/37/39-S45

AG3150000

Xn

Stable under recommended storage conditions.

P201-P261-P280-P284-P304 + P340-P308 + P313

H302-H317-H319-H334-H341-H350i-H360F-H410

SRP: Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in air, soil or water; effects on animal, aquatic and plant life; and conformance with environmental and public health regulations. If it is possible or reasonable use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination.|Product: Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber; Contaminated packaging: Dispose of as unused product.|Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. (Extra personal protection: P2 filter respirator for harmful particles.) Do NOT let this chemical enter the environment. /Tetrahydrate ("The recommendations on this Card also apply to Cobalt (II) acetate anhydrous (CAS 71-48-7).")/

Reacts with strong oxidants causing fire and explosion hazard. /Tetrahydrate ("The recommendations on this Card also apply to Cobalt (II) acetate anhydrous (CAS 71-48-7).")/

Cobaltous acetate is an indirect food additive for use only as a component of adhesives.|Trace minerals added to animal feeds. These substances added to animal feeds as nutritional dietary supplements are generally recognized as safe when added at levels consistent with good feeding practice. All substances listed may be in anhydrous or hydrated form. Cobalt acetate is included on this list.

Special Hazards of Combustion Products: Toxic cobalt oxide fumes may form in fire. (USCG, 1999)

|Danger|H317: May cause an allergic skin reaction [Warning Sensitization, Skin]|P201, P202, P261, P272, P273, P280, P281, P285, P302+P352, P304+P341, P308+P313, P321, P333+P313, P342+P311, P363, P391, P405, and P501|H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]|Aggregated GHS information provided by 2758 companies from 27 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H302: Harmful if swallowed [Warning Acute toxicity, oral]|P201, P202, P260, P261, P264, P270, P272, P273, P280, P281, P285, P301+P312, P302+P352, P304+P341, P305+P351+P338, P308+P313, P314, P321, P330, P333+P313, P337+P313, P342+P311, P363, P391, P405, and P501|P201, P202, P261, P264, P270, P272, P273, P280, P281, P285, P301+P312, P302+P352, P304+P341, P305+P351+P338, P308+P313, P321, P330, P333+P313, P337+P313, P342+P311, P363, P391, P405, and P501|P201, P202, P260, P261, P264, P270, P271, P272, P280, P281, P285, P301+P312, P302+P352, P304+P340, P304+P341, P305+P351+P338, P308+P313, P309+P311, P312, P314, P321, P330, P333+P313, P337+P313, P342+P311, P363, P403+P233, P405, and P501

Dust respirator; rubber gloves; goggles or face shield; protective clothing (USCG, 1999)|Eye/face protection: Face shield and safety glasses. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).|Skin protection: Handle with gloves.|Body Protection: Complete suit protecting against chemicals. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.|Respiratory protection: Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).|Local exhaust or breathing protection. Protective gloves. Protective clothing. Safety goggles, or eye protection in combination with breathing protection. /Tetrahydrate ("The recommendations on this Card also apply to Cobalt (II) acetate anhydrous (CAS 71-48-7).")/

Reacts with strong oxidants causing fire and explosion hazard. /Tetrahydrate ("The recommendations on this Card also apply to Cobalt (II) acetate anhydrous (CAS 71-48-7).")/

Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.|Advice for firefighters: Wear self-contained breathing apparatus for firefighting if necessary.|In case of fire in the surroundings: use appropriate extinguishing media. /Tetrahydrate ("The recommendations on this Card also apply to Cobalt (II) acetate anhydrous (CAS 71-48-7).")/

ACCIDENTAL RELEASE MEASURES: Personal precautions, protective equipment and emergency procedures: Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up: Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.|Liquid material spills can be copiously flushed with water and channeled to a treatment system or holding tank for reclamation or proper disposal. Spills of dry material can be removed by vacuuming or wet mopping. Some spills can be removed by hosing, first with a mist of water to dampen the spilled material and then with a more forceful stream that flushes it into a holding tank or other facility for handling contaminated water. Work surfaces or contaminated clothing should never be cleaned by dry sweeping or blowing with pressurized hoses. Recovery systems used to reclaim waste metals should comply with federal, state, and local regulations. All waste materials generated in the handling of cobalt-containing substances should be disposed of in compliance with federal, state, and local regulations. /Cobalt and cobalt salts/

SRP: The scientific literature for the use of contact lenses by industrial workers is inconsistent. The benefits or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.|SRP: Local exhaust ventilation should be applied wherever there is an incidence of point source emissions or dispersion of regulated contaminants in the work area. Ventilation control of the contaminant as close to its point of generation is both the most economical and safest method to minimize personnel exposure to airborne contaminants. Ensure that the local ventilation moves the contaminant away from the worker.|ACCIDENTAL RELEASE MEASURES: Personal precautions, protective equipment and emergency procedures: Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.|Precautions for safe handling: Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Further processing of solid materials may result in the formation of combustible dusts. The potential for combustible dust formation should be taken into consideration before additional processing occurs. Provide appropriate exhaust ventilation at places where dust is formed.|For more Preventive Measures (Complete) data for Cobaltous acetate (11 total), please visit the HSDB record page.

The substance is irritating to the eyes, the skin and the respiratory tract. /cobalt (II) acetate tetrahydrate/

Listed as a hazardous air pollutant (HAP) generally known or suspected to cause serious health problems. The Clean Air Act, as amended in 1990, directs EPA to set standards requiring major sources to sharply reduce routine emissions of toxic pollutants. EPA is required to establish and phase in specific performance based standards for all air emission sources that emit one or more of the listed pollutants. Cobaltous acetate is included on this list.

IDENTIFICATION AND USE: Cobaltous acetate is a solid. It is used as a bleaching agent and drier for lacquers, varnishes; in anodizing; and as a catalyst for oxidation and esterification. Mineral supplement in cattle feed. HUMAN EXPOSURE AND TOXICITY: Acute human exposure led to vomiting, severe pain and tenderness in epigastrium, pain in limbs with marked weakness, hematemesis, and occult blood in stools. DNA strand breaks accumulated and repair was inhibited in irradiated HeLa cells exposed to cobaltous acetate. ANIMAL STUDIES: Following administration to rats by gastric intubation acute effects included sedation, diarrhea, and decreased body temperature. Gross pathology exam revealed hemorrhages and dystrophic changes in the liver, kidney, and heart. Oral exposure in rats led to increase in the hemoglobin and hematocrit as well as in the plasma proteins. There was significant hyperglycemia and also significant changes in the lipid parameters such as triglycerides and cholesterol. The neurological signs were observed in rats after acute cobaltous acetate intoxication under mild ischemic conditions. It was not reported to be teratogenic in hamsters or rats. Oxidative DNA base damage has been described.

LD50 Mouse iv 31 mg/kg|LD50 Rabbit i.v. 25 mg/kg|LD50 Rat oral 503 mg/kg /Cobalt (II) acetate/|LD50 Rats oral 133 mg Co/kg|LD50 Rats ip 10.6 mg Co/kg

Cobaltous acetate's production and use in the manufacture of drying agents for inks, paints and varnishes, in anodizing(1-3), as a catalyst, and as a mineral supplement in animal feed additives(2,4) may result in its release to the environment through various waste streams(SRC).

ATMOSPHERIC FATE: Inorganic cobalt compounds are nonvolatile and released into the atmosphere in particulate form(1). Particulate-phase cobalt compounds are removed from the air by wet and dry deposition(SRC). Cobalt has been detected in atmospheric deposition(2) and in rain-snow precipitation(3).

Food Chain Concentration Potential of cobaltous acretate tetrahydrate: Bioconcentration of 200-1000 fold only under constant exposure. Not significant in spill condition(1).

Evaporation of cobaltous acetate tetrahydrate at 20 °C is negligible(1).

According to the 2012 TSCA Inventory Update Reporting data, 5 reporting facilities estimate the number of persons reasonably likely to be exposed during the manufacturing, processing, or use of cobaltous acetate in the United States may be as low as 10-24 workers and as high as 50-99 workers per plant; the data may be greatly underestimated due to confidential business information (CBI) or unknown values(1).|NIOSH (NOES Survey 1981-1983) has statistically estimated that 6,143 workers (629 of these are female) are potentially exposed to cobaltous acetate tetrahydrate in the US(1). Occupational exposure to cobaltous acetate may occur through inhalation of dust and dermal contact with this compound at workplaces where cobaltous acetate is produced or used(SRC). Although available for use in animal feed supplements, cobaltous acetate is prohibited from direct addition or use in human feeds(2); cobaltous acetate is permitted for indirect food contact applications including adhesives for use in packaging, transporting, or holding food and as a components of paper and paperboard in contact with aqueous and fatty foods(2). Former use as a foam stabilizer in malt beverages is now prohibited(2) which eliminates human exposure through ingestion of treated beverages(SRC). Use data indicate that the general population may be exposed to cobaltous acetate via dermal contact with consumer products containing cobaltous acetate(SRC).

Absorption from the GI tract in rats was found to vary between 11 and 34% depending on administered dose value. The highest concn was found in the liver, a low concn was noted in the kidney, pancreas, and spleen.|The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. /Tetrahydrate ("The recommendations on this Card also apply to Cobalt (II) acetate anhydrous (CAS 71-48-7).")/

Inhalation causes shortness of breath and coughing; permanent disability may occur. Ingestion causes pain and vomiting. Contact with eyes causes irritation. Contact with skin may cause dermatitis. (USCG, 1999)

INHALATION: move to fresh air; if breathing has stopped, begin artificial respiration. INGESTION: give large amounts of water; induce vomiting. EYES: flush with water for at least 15 min. SKIN: wash with soap and water. (USCG, 1999)

/SRP:/ Immediate First Aid: Ensure that adequate decontamination has been carried out as needed. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (Head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Cobalt and Related Compounds/|/SRP:/ Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if needed. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 mL of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal ... . /Cobalt and Related Compounds/|/SRP:/ Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in respiratory arrest. Positive pressure ventilation techniques with a bag valve mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Consider administering a beta agonist such as albuterol for severe bronchospasm... . Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start IV administration of D5W TKO (to keep open). Use 0.9% saline (NS) or lactated Ringer's if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Cobalt and Related Compounds/|First Aid: INHALATION: Fresh air, rest. Refer for medical attention. SKIN: Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention. EYES: First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor. INGESTION: Rinse mouth. Refer for medical attention.

/HUMAN EXPOSURE STUDIES/ Repeated or prolonged contact may cause skin sensitization. Repeated or prolonged inhalation exposure may cause asthma. Lungs may be affected by repeated or prolonged exposure. The substance may have effects on the heart, thyroid, bone marrow, when ingested.|/HUMAN EXPOSURE STUDIES/ The substance is irritating to the eyes, the skin and the respiratory tract. /cobalt (II) acetate tetrahydrate/|/SIGNS AND SYMPTOMS/ Gastric disturbance, symptoms occurring shortly after leaving work, involving inhalation of dry powdered cobalt acetate ... included vomiting, severe pain and tenderness in epigastrium, pain in limbs with marked weakness and on 3rd day some hematemesis, occult blood in stools.|/SIGNS AND SYMPTOMS/ ...a man grinding cobalt in a /poorly/ ventilated room /developed/ the symptoms /which/ were predominantly gastric but also included hematuria.|For more Human Toxicity Excerpts (Complete) data for Cobaltous acetate (6 total), please visit the HSDB record page.

cobalt(II) acetate

Technical, pure crystals, CP /chemically pure/.|Liquid, crystal grades; soln and crystal form, technical and reagent grade

All other basic organic chemical manufacturing|Acetic acid, cobalt(2+) salt (2:1): ACTIVE