N-Ethyl-4-methylbenzenesulfonamide
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N-Ethyl-4-methylbenzenesulfonamide
structure -
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CAS No:
80-39-7
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Formula:
C9H13NO2S
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Chemical Name:
N-Ethyl-4-methylbenzenesulfonamide
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Synonyms:
Benzenesulfonamide,N-ethyl-4-methyl-;p-Toluenesulfonamide,N-ethyl-;N-Ethyl-4-methylbenzenesulfonamide;N-Ethyl-p-toluenesulfonamide;p-Toluene-N-ethylsulfonamide;p-Toluenesulfonyl-N-ethylamide;Santicizer 3;N-Tosylethylamine;N-Ethyl-p-tolylsulfonamide;N-Ethyl-p-methylbenzenesulfonamide;N-Ethyltosylamide;NSC 68803;N-Ethyl-4-toluenesulfonamide;825629-31-0
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CAS No:
Description
off-white crystalline solid
Platelets (from dilute alcohol or ligroin) or off-white solid. (NTP, 1992)|Toluene ethylsulfonamide is a viscous slightly yellow liquid. (NTP, 1992)|Liquid
Platelets (from dilute alcohol or ligroin) or off-white solid. (NTP, 1992)|Toluene ethylsulfonamide is a viscous slightly yellow liquid. (NTP, 1992)
N-Ethyl-4-methylbenzenesulfonamide Basic Attributes
199.27
199.27
201-275-1
992S798SJB
68803
DTXSID5025310
2935009090
Characteristics
54.6
1.6
Platelets (from dilute alcohol or ligroin) or off-white solid. (NTP, 1992)
1.203 at 63.9° F (NTP, 1992)
64 °C
208 °C745 mm Hg(lit.)
greater than 200° F (NTP, 1992)
1.527
less than 0.1 mg/mL at 64° F (NTP, 1992)
Store below +30°C.
4.15 mm Hg at 77° F (NTP, 1992)
Insoluble in water.
Amines, Phosphines, and Pyridines|Amides and Imides
An amide. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).|TOLUENE ETHYLSULFONAMIDE is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Safety Information
NONH for all modes of transport
3
36/37/38
26-36/37
Xi
Stable. Incompatible with strong oxidizing agents.
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
H315
Flash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)|This chemical is probably combustible. (NTP, 1992)
|Warning|H315 (98.39%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 80 companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H336 (91.07%): May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]|P261, P271, P304+P340, P312, P403+P233, P405, and P501|Aggregated GHS information provided by 110 companies from 4 notifications to the ECHA C&L Inventory.
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
SMALL SPILLS AND LEAKAGE: Should a spill occur while you are handling this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with 60-70% ethanol and transfer the dampened material to a suitable container. Use absorbent paper dampened with 60-70% ethanol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should store this material under ambient temperatures. (NTP, 1992)|SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should store this material in a refrigerator. STORE AWAY FROM SOURCES OF IGNITION. (NTP, 1992)
RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)
Drug Information
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)
N-ethyl-4-toluenesulfonamide
N-Ethyl-4-methylbenzenesulfonamide Use and Manufacturing
Can be used in organic synthesis, pharmaceuticals, and as a plasticizer
Plasticizers
Ink, toner, and colorant products
25,000 - 100,000 lb
Plastics product manufacturing|Benzenesulfonamide, N-ethyl-4-methyl-: ACTIVE
Cosmetics -> Film forming; Plasticiser
Computed Properties
Molecular Weight:199.27
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:199.06669983
Monoisotopic Mass:199.06669983
Topological Polar Surface Area:54.6
Heavy Atom Count:13
Complexity:235
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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N-Ethyl-4-methylbenzenesulfonamide
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