 Home > Encyclopedia > α-Kainic acid

α-Kainic acid

α-Kainic acid structure

CAS No:
487-79-6
Formula:
C10H15NO4
Chemical Name:
α-Kainic acid
Synonyms:
3-Pyrrolidineacetic acid,2-carboxy-4-(1-methylethenyl)-,(2S,3S,4S)-;3-Pyrrolidineacetic acid,2-carboxy-4-isopropenyl-;3-Pyrrolidineacetic acid,2-carboxy-4-(1-methylethenyl)-,[2S-(2α,3β,4β)]-;(2S,3S,4S)-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid;Digenin;Helminal;α-Kainic acid;Digenic acid;L-α-Kainic acid;(-)-α-Kainic acid;(2S,3S,4S)-2-Carboxy-4-isopropenylpyrrolidine-3-acetic acid;(-)-Kainic acid;Kainic acid;4071-38-9;46398-96-3

Description

Kainic acid is a potent agonist at excitatory amino acid receptor subtypes in the CNS.

Kainic acid is a dicarboxylic acid, a pyrrolidinecarboxylic acid, a L-proline derivative and a non-proteinogenic L-alpha-amino acid. It has a role as an antinematodal drug and an excitatory amino acid agonist. It is a conjugate acid of a kainate(1-).|(2S-(2 alpha,3 beta,4 beta))-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid. Ascaricide obtained from the red alga Digenea simplex. It is a potent excitatory amino acid agonist at some types of excitatory amino acid receptors and has been used to discriminate among receptor types. Like many excitatory amino acid agonists it can cause neurotoxicity and has been used experimentally for that purpose.

α-Kainic acid Basic Attributes

Molecular Weight：

213.23

Exact Mass：

213.23

UNII：

SIV03811UC

NSC Number：

136038

DSSTox ID：

DTXSID7040526

Characteristics

PSA：

86.6

XLogP3：

-1.8

Density：

1.2±0.1 g/cm3

Melting Point：

251 °C (decomp)

Flash Point：

219.8±28.7 °C

Refractive Index：

1.509

Collision Cross Section：

144.2 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Safety Information

wgk germany：

hazard class code：

R20/21/22

safety instructions：

22-24/25-36

RTECS Number：

UX9665250

Marks：

Drug Information

MeSH：

Drugs that bind to and activate excitatory amino acid receptors. (See all compounds classified as Excitatory Amino Acid Agonists.)|Substances used in the treatment or control of nematode infestations. They are used also in veterinary practice. (See all compounds classified as Antinematodal Agents.)

MeSH Entry Terms：

Acid, Digenic

α-Kainic acid Use and Manufacturing

excitory amino acid, neurotoxin, neurobiology tool Neurobiological tool. glutamate receptor agonist, anthelmintic

Computed Properties

Molecular Weight:213.23
XLogP3:-1.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:213.10010796
Monoisotopic Mass:213.10010796
Topological Polar Surface Area:86.6
Heavy Atom Count:15
Complexity:300
Defined Atom Stereocenter Count:3
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Learn More Other Chemicals

Hot Searches: ethoxide; nitrohydrochloric acid; sodium hypobromite; dimethyl terephthalate; benzyl bromide; bioglutide

Guide of α-Kainic acid

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Learn More Other Chemicals

α-Kainic acid

SDS

Request for Quotation



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.