 Home > Encyclopedia > Mersalyl

Mersalyl

Mersalyl structure

CAS No:
492-18-2
Formula:
C13H16HgNO6.Na
Chemical Name:
Mersalyl
Synonyms:
Mercurate(1-),[3-[[2-(carboxylatomethoxy)benzoyl-κO]amino]-2-methoxypropyl-κC]hydroxy-,sodium (1:1);Mercury,[3-(α-carboxy-o-anisamido)-2-methoxypropyl]hydroxy-,monosodium salt;Mercurate(1-),[3-[[2-(carboxylatomethoxy)benzoyl]amino]-2-methoxypropyl]hydroxy-,sodium;Mercurate(1-),[3-[[2-(carboxylatomethoxy)benzoyl-κO]amino]-2-methoxypropyl-κC]hydroxy-,sodium;Acetic acid,[2-[[(2-methoxypropyl)amino]carbonyl]phenoxy]-,mercury complex;Diursal;Igrosin;Mercuramide;Mercurital;Mercusal;Mersalyl;Salurin;Salyrgan;Sodium [o-[[3-(hydroxymercuri)-2-methoxypropyl]carbamoyl]phenoxy]acetate;Sodium mersalyl;Uragan;Sodium O-[(3-hydroxy mersalyl-2-methoxypropyl)-carbamoyl]phenoxyacetic acetic acid;Sodium O-[(3-hydroxymercuri-2-methoxypropyl)-carbamyl]-phenoxy acetic acid;Mersalyl acid sodium salt;Salirgan;Mersalin;64615-74-3;856355-52-7
Categories:
Active Pharmaceutical Ingredients > Urinary System Drugs

Description

A toxic thiol mercury salt formerly used as a diuretic. It inhibits various biochemical functions, especially in mitochondria, and is used to study those functions.

Mersalyl Basic Attributes

Molecular Weight：

505.85

Exact Mass：

507.05800

EC Number：

207-748-9

ATC Code：

C - Cardiovascular system

Characteristics

PSA：

88.7

Toxicity：

LD50 i.v. in mice, rats: 72.6, 17.7 mg/kg (Robbins, Chen)

Safety Information

Packing level：

Hazard category：

6.1(a)

Transport codes：

2025

Drug Information

MeSH：

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. (See all compounds classified as Enzyme Inhibitors.)

MeSH Entry Terms：

Acid, Mersalyl

Mersalyl Use and Manufacturing

Use Classification：

Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients

Computed Properties

Molecular Weight:506.86
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:9
Exact Mass:508.066000
Monoisotopic Mass:508.066000
Topological Polar Surface Area:88.7
Heavy Atom Count:22
Complexity:334
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes