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Sciadopitysin

Sciadopitysin structure

Sciadopitysin 

structure
  • CAS No:

    521-34-6

  • Formula:

    C33H24O10

  • Chemical Name:

    Sciadopitysin

  • Synonyms:

    4H-1-Benzopyran-4-one,5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-2-(4-methoxyphenyl)-;3′′′,8-Biflavone,5,5′′,7-trihydroxy-4′,4′′′,7′′-trimethoxy-;Sciadopitysin;5,7-Dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one;7,4′,4′′′-Trimethylamentoflavone;NSC 45108

  • Categories:

    Natural Products  >  Flavonoids

Description

Sciadopitysin is a type of biflavonoids in leaves from ginkgo biloba[1]. Sciadopitysi inhibits RANKL-induced osteoclastogenesis and bone loss by inhibiting NF-κB activation and reducing the expression of c-Fos and NFATc1[2].


Sciadopitysin is a biflavonoid that is a 7, 4', 4'''-trimethyl ether derivative of amentoflavone. It has a role as a bone density conservation agent and a platelet aggregation inhibitor. It is a biflavonoid, a hydroxyflavone, a methoxyflavone and a ring assembly. It derives from an amentoflavone.

Sciadopitysin Basic Attributes

580.54

580.54

208-311-5

WL44VY201L

45108

DTXSID30200096

29329990

Characteristics

141

5.50

1.4±0.1 g/cm3

286-287 °C (decomp)

839.6±65.0 °C at 760 mmHg

276.2±27.8 °C

1.684

Safety Information

24/25

Drug Information

sciadopitysin

Sciadopitysin Use and Manufacturing

Polyketides [PK] -> Flavonoids [PK12] -> Biflavonoids and polyflavonoids [PK1204]

Computed Properties

Molecular Weight:580.5
XLogP3:6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:6
Exact Mass:580.13694696
Monoisotopic Mass:580.13694696
Topological Polar Surface Area:141
Heavy Atom Count:43
Complexity:1100
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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