Dibenzo[b,def]chrysene-7,14-dione

332.35088

332.35

204-903-2

8XO6A4G496

30987

DTXSID6021454

2914399090

34.14000

5.26260

C.i. vat yellow 4 is a viscous orange liquid. Used for coloring of cotton, wool and cellulose acetate.

1.418 g/cm3

385 °C

606.7ºC at 760 mmHg

219.9ºC

1.792

greater than or equal to 100 mg/mL at 75° F (NTP, 1992)

1.15E-14mmHg at 25°C

Water soluble.

Hydrocarbons, Aromatic

C.I. VAT YELLOW 4 reacts very readily with reducing agents to give a colorless or nearly colorless product. Subsequent oxidation then restores the color.

Stable. Combustible. Incompatible with strong oxidizing agents.

REVIEW OF INHALATION (TOTAL-BODY-EXPOSURE) STUDIES OF COLORED CHEM SMOKES. ACUTE TOXICITIES, TIME TO DEATHS, & GROSS SIGNS COMPARED. TOXICOLOGICAL EVALUATION OF DYES IN SMOKE MIXT INCL. ONE OF THE DYES USED IN CHEM SMOKES IS DIBENZO(B,DEF)CHRYSENE-7,14-DIONE.[OWENS EJ, WARD DM; USNTIS AD/A REP ISS NO 003827/3GA 72 PP (1974)]|DHEW/NCI; Bioassay of C.I. Vat Yellow 4 for Possible Carcinogenicity (1979) Technical Rpt Series No. 134 DHEW Pub No. (NIH) 79-1389

This chemical is probably combustible. (NTP, 1992)

Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)

SMALL SPILLS AND LEAKAGE: If you should spill this chemical, use absorbent paper to pick up all liquid spill material. Seal the absorbent paper, as well as any of your clothing which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Wash any surfaces you may have contaminated with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should store this material under ambient temperatures. (NTP, 1992)

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter). (NTP, 1992)

FISCHER 344 RATS OF EACH SEX ADMIN FORMULATED PRODUCT CONTAINING CI VAT YELLOW 4 IN DIET FOR 104 WK OR 106 WK @ 3500 OR 7000 PPM. TUMOR INCIDENCE WAS NOT HIGHER THAN THAT OF CONTROLS.|B6C3F1 MICE ADMIN FORMULATED PRODUCT CONTAINING CI VAT YELLOW 4 IN DIET FOR 104 WK OR 106 WK, (25,000 OR 50,000 PPM FOR MALES & 12,500 OR 25,000 PPM FOR FEMALES). IT WAS CARCINOGENIC FOR MALES, BUT NOT FEMALES, INDUCING LYMPHOMAS.

1.91e+04 L/kg

Beauticians exposed to paraphenylenediamine derivatives in hair dyes, workers dyeing texitle resins, and photographic film developers exposed to color developing solutions not infrequently become sensitized to azo dyes. /Organic dyes/

ACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits acrid smoke and irritating fumes. (NTP, 1992)

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. OTHER: Since this chemical is a known or suspected carcinogen you should contact a physician for advice regarding the possible long term health effects and potential recommendation for medical monitoring. Recommendations from the physician will depend upon the specific compound, its chemical, physical and toxicity properties, the exposure level, length of exposure, and the route of exposure. (NTP, 1992)

Most organic azo dyes are potential skin sensitizers, the most important of which are paraphenylenediamine and its analogs. Water soluble azo dyes are more likely to cause clinical sensitization than insoluble dyes. ... In addition to allergic eczematous contact dermatitis, color developing solutions have caused lichen planus like eruptions. /Organic dyes/

dibenzo(b,def)chrysene-7,14-dione

ESSENTIALLY 100% AS A DYE

Dibenzo[b,def]chrysene-7,14-dione: ACTIVE

RAPID & SIMPLE METHOD DESCRIBED FOR ANAL OF POLYCYCLIC QUINONES IN AIR DERIVED FROM POLYNUCLEAR AROMATIC HYDROCARBONS INVOLVING RESOLUTION BY COLUMN & THIN-LAYER CHROMATOGRAPHY & SPECTRAL ANAL BY UV, VISIBLE & FLUORESCENCE SPECTROPHOTOMETRY, & MASS SPECTROMETRY.