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7-Methylguanine

7-Methylguanine structure

7-Methylguanine 

structure
  • CAS No:

    578-76-7

  • Formula:

    C6H7N5O

  • Chemical Name:

    7-Methylguanine

  • Synonyms:

    6H-Purin-6-one,2-amino-1,7-dihydro-7-methyl-;Guanine,7-methyl-;2-Amino-1,7-dihydro-7-methyl-6H-purin-6-one;7-Methylguanine;N7-Methylguanine;2-Amino-7-methylhypoxanthine;NSC 193444;NSC 19647;2-Amino-7-methyl-7H-purin-6-ol;2-Amino-7-methyl-1H-purin-6(7H)-one;2-Imino-7-methyl-2,3,6,7-tetrahydro-1H-purin-6-one;2-Amino-7-methyl-3H-purin-6-one;2-Amino-7-methyl-6,7-dihydro-3H-purin-6-one;2-Amino-7-methyl-6,7-dihydro-1H-purin-6-one;126605-68-3;6970-99-6;155125-43-2

  • Categories:

    Biochemical Engineering  >  Nucleoside Drugs

Description

7-Methylguanine is a metabolite of DNA methylation. It can be generated by methylating agents, and used as a probe of protein–DNA interactions and a key component of DNA sequencing method.

7-Methylguanine Basic Attributes

165.15

165.15

209-431-0

Characteristics

85.3

-1.2

Solid

1.8±0.1 g/cm3

370 °C

503.9°C at 760 mmHg

244.9±26.5 °C

1.865

−20°C

Safety Information

3

MF8464000

7-Methylguanine Use and Manufacturing

Has binding affinity to guanine deaminase, an important metalloenzyme in purine catabolism. Found in urine of patients with malignant cancer.

Material

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