2-Trifluoromethylphenylboronic acid
-
2-Trifluoromethylphenylboronic acid
structure -
-
CAS No:
1423-27-4
-
Formula:
C7H6BF3O2
-
Chemical Name:
2-Trifluoromethylphenylboronic acid
-
Synonyms:
Boronic acid,B-[2-(trifluoromethyl)phenyl]-;o-Tolueneboronic acid,α,α,α-trifluoro-;Boronic acid,[2-(trifluoromethyl)phenyl]-;B-[2-(Trifluoromethyl)phenyl]boronic acid;2-Trifluoromethylbenzeneboronic acid;2-Trifluoromethylphenylboronic acid;1695577-90-2;2093414-94-7
- Categories:
-
CAS No:
Characteristics
40.5
0.38520
white to light beige crystalline powder
1.4±0.1 g/cm3
106-107 °C
274.5°C at 760 mmHg
119.8±30.1 °C
1.462
0-6ºC
Safety Information
NONH for all modes of transport
3
R36/37/38
S37/39-S26
Xi:Irritant
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
H315
|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 9 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
2-Trifluoromethylphenylboronic acid Use and Manufacturing
In 250 ml three-mouth reaction flask, add 2.3 g magnesium chips, then heating and drying under the protection of nitrogen. Then 0.1 g iodine, 12.8 g bis(dimethylamino)chloroborane and 30 ml tetrahydrofuran were added to the reaction flask. Then start to drop 2.4 g 2-chloro(trifluoromethyl)benzene and 20 ml tetrahydrofuran mixed solution, stir for half an hour. Continue to drop 12.0 g of 2-chloro(trifluoromethyl)benzene and 100 ml tetrahydrofuran mixed solution. The solution temperature maintained at 20 - 30 degrees. After 2 hours addition completed. Then the mixed solution is cooled to 0 degrees, add 50 ml saturated ammonium chloride solution, continuously stirred for 1 hour. Allow to stand to separate the phases. To the aqueous phase, use 70 ml ethyl acetate to extract. The combined organic layer, for drying of magnesium sulfate, concentrated under reduced pressure. For the residue 80 mL65 °C hot ethyl acetate dissolved, then in 2 hours to cool down to room temperature, and then the 1 hours by adding 300 ml of normal hexane, stirring 3 hours, filtering to obtain 7.9 g white solid 2-trifluoromethylphenylboronic acid, yield 52percent.Part A. Part A.
Computed Properties
Molecular Weight:189.93
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:190.0412941
Monoisotopic Mass:190.0412941
Topological Polar Surface Area:40.5
Heavy Atom Count:13
Complexity:172
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of 2-Trifluoromethylphenylboronic acid
-
![China]()
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives -
![China]()
CN
4 YRS
Business licensedTrader Supplier of Fluorine containing fine chemicals PharmaceuticalInquiryCAS No.: 1423-27-4Content: 99%
Learn More Other Chemicals
-
3,5-DIBROMO-2-[[[(3,5-DINITROBENZOYL)AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID
535965-38-9
-
3,5-DIBROMO-2-[[[[(2-CHLOROPHENOXY)ACETYL]AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID
532386-89-3
-
3,5-DIBROMO-2-[[[(4-METHYL-3-NITROBENZOYL)AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID
532943-48-9
-
3,5-DIBROMO-2-[[[[3-(2-FURANYL)-1-OXO-2-PROPENYL]AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID Formula
586392-09-8
-
3,5-DIBROMO-2-[[[[(2-METHYLPHENOXY)ACETYL]AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID Formula
531548-30-8
-
2-(1,8-dibromo-16,18-dioxo-17-azapentacyclo[6.6.5.0~2,7~.0~9,14~.0~15,19~]nonadeca-2,4,6,9,11,13-hexaen-17-yl)benzoic acid Formula
333340-54-8
-
3,5-DIBROMO-2-[[[[3-(PHENOXYMETHYL)BENZOYL]AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID Structure
586393-79-5
-
3,5-DIBROMO-2-[[[(4-CHLOROBENZOYL)AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID Structure
531530-32-2
-
What is 2-Cyclopentyl-3-(2,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-oxo-4-isoquinolinecarboxylic acid
400073-92-9
-
What is 9-Octadecenoic acid (9Z)-, compd. with N,N-dimethylcyclohexanamine (1:1)
65122-23-8
2-Trifluoromethylphenylboronic acid
SDSRequest for Quotation