 Home > Encyclopedia > Dutasteride

Dutasteride

Dutasteride structure

CAS No:
164656-23-9
Formula:
C27H30F6N2O2
Chemical Name:
Dutasteride
Synonyms:
1H-Indeno[5,4-f]quinoline-7-carboxamide,N-[2,5-bis(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-,(4aR,4bS,6aS,7S,9aS,9bS,11aR)-;4-Azaandrost-1-ene-17-carboxamide,N-[2,5-bis(trifluoromethyl)phenyl]-3-oxo-,(5α,17β)-;(4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-[2,5-Bis(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide;GG 745;Dutasteride;GI 198745;Avodart;Veltride;Avolve;(5α,17β)-N-[(2,5-Bis(trifluoromethyl)phenyl]-3-oxo-4-aza-5-androst-1-ene-17-carboxamide
Categories:
Active Pharmaceutical Ingredients > Hormones and the Endocrine System

Description

Dutasteride is well tolerated and the most occurring adverse events are impotence, decrease in libido, ejaculation disorders and gynaecomastia. Unlike a-blockers which primarily act acutely on benign prostatic hyperplasia symptoms, 5a-reductase inhibitors can alter disease progression. Concomitant administration of dutasteride did not affect the pharmacokinetics of either tamsulosin or terazosin. In addition, the tolerability of both terazosin and tamsulosin were improved during combinati

Dutasteride Basic Attributes

Molecular Weight：

528.53

Exact Mass：

528.53

EC Number：

1308068-626-2

HScode：

2937290000

Characteristics

PSA：

58.2

XLogP3：

5.4

Appearance：

white to beige

Density：

1.303±0.06 g/cm3(Predicted)

Melting Point：

254-258 °C

Boiling Point：

620.3±55.0 °C(Predicted)

Flash Point：

329.0±31.5 °C

Refractive Index：

1.523

Water Solubility：

DMSO: soluble2mg/mL, clear

Storage Conditions：

-20°C Freezer

Vapor Pressure：

0mmHg at 25°C

Safety Information

Transport codes：

NONH for all modes of transport

Precautionary statement(s)：

P201, P202, P273, P281, P308+P313, P391, P405, P501

Hazard Statements：

H360

Dutasteride Use and Manufacturing

Dutasteride is a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.

Drug Function and Efficacy

No specific pharmacological effects mentioned

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Dutasteride soft capsules
Ingredients	The main ingredient of this product is dutasteride. Molecular formula: C27H30F6N2O2 Molecular weight: 528.5297
Indication	If used with other drugs, drug interactions may occur. Please consult your doctor or pharmacist for details.
Specifications	0.5 mg

Dutasteride soft capsules
Ingredients	The main ingredient of this product is dutasteride. Molecular formula: C27H30F6N2O2 Molecular weight: 528.5297
Specifications	0.5 mg

Dutasteride soft capsules
Ingredients	The main ingredient of this product is dutasteride.
Indication	See instructions for details.
Specifications	0.5mg*10 tablets/box

Registered Holders

MSN LABORATORIES PRIVATE LTD

United States
Active
HETERO LABS LTD

United States
Active
APITORIA PHARMA PRIVATE LTD

United States
Active

See More Registered Holders

Recommended Suppliers of Dutasteride

Hangzhou Dawn Ray Pharmaceutical Co.,Ltd Contact Supplier

CN
5 YRS

Business licensed Certified factory

Manufactory Supplier of D-Biotin,Tobramycin base,L(-)-Carnitine base,Polymyxin B sulfate USP,Kanamycin sulfate monohydrate,Finasteride 99% USP

Dutasteride Chinese supplier pharmacetical

CAS No.: 164656-23-9

Inquiry
Shaanxi Dideu Medichem Co. Ltd Contact Supplier

CN
4 YRS

Business licensed Certified factory

Manufactory Supplier of Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst,Chemical Materials,Chem&Pharm Intermediates,Organic Intermediates,Feed Additive

dutasteride-164656-23-9-Drum-25kg-Pharmacy Grade-Preserve in well-closed, light-resistant and airtight containers.

CAS No.: 164656-23-9

Grade: Pharmaceutical Grade

Content: 99%

Inquiry
Hebei Longbang Technology Co., Ltd Contact Supplier

CN
2 YRS

Business licensed

Trader Supplier of chemical

CAS 164656-23-9 Dutasteride Bulk drug: prostaglandins

CAS No.: 164656-23-9

Grade: Chemical Grade

Content: 99%

Inquiry
Mobel Biomaterials Technology Co.,ltd Contact Supplier

CN
4 YRS

Business licensed

Trader Supplier of Peptide supplements,Cosmetic peptides,Cosmetic raw materials,Peptide

Dutasteride Powder CAS 164656-23-9 steroids raw BP USP Standard High pure

Unit Price: $1-1.2 /G EXW

CAS No.: 164656-23-9

Grade: Pharmaceutical Grade

Content: 99.0%

Inquiry
Creative Enzymes Contact Supplier

US
6 YRS

Business licensed Certified factory

Manufactory Supplier of Coenzymes,Inhibito,Enzymes,Zymogens,Substrates

Dutasteride

CAS No.: 164656-23-9

Content: 99%

Inquiry