Wild blueberry extract may affect the body's blood vessel formation

Recently, in a research report published in the International Journal of Medicinal Food, scientists from the University of Maine and other institutions found through research that wild blueberry extract may affect the formation of blood vessels in the body. When the body experiences damage, cells take action, the emergence of new blood vessels occurs through a process called angiogenesis, and the cells also migrate in a coordinated healing process.

The ability to control these mechanisms may potentially accelerate the treatment of various diseases such as cancer and wound healing. Polyphenols are a class of natural biologically active compounds that exist in specific plants. They can often be used as candidate compounds to enhance or slow down the progress of diseases. . The low-bush blueberry grown in eastern Maine is one of the richest sources of polyphenols known; in the article, the researchers identified the concentration of these wild blueberry polyphenols that affect cell migration The process of blood vessels and inflammation, and the researchers also clarified how to apply this polyphenol compound to the clinical environment.

The researchers said that we evaluated how two polyphenol compounds found in wild blueberries: anthocyanins and phenolic acids affect blood vessel formation, gene expression and protein synthesis. All of these factors It is an important factor in the tissue healing process. In addition, researchers have found that different extracts and different concentrations of compounds may be used to increase or decrease its activity in cell culture.

Researchers aim to develop a new prototype therapy to enhance wound healing and tissue regeneration, so as to treat hard-to-treat wounds such as burns, or the treatment of patients with poor circulation due to previous diseases such as diabetes; biomedical research The staff is also currently researching the potential of wild blueberry polyphenols to reduce inflammation, because inflammation is directly related to the occurrence of a wide range of chronic diseases, including obesity and heart disease.

Finally, the researcher Klimis-Zacas said that the relevant research results may help researchers analyze the different effects of these biologically active compounds in in vitro models, and allow researchers to verify their functions in preclinical studies and develop clinical applications. Biomedical prototype. Later researchers will continue to conduct in-depth research to clarify the molecular mechanism of polyphenols in wild blueberries that affect the body's angiogenesis.