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The EU reviews the current maximum residue level for dithinon

 foodmate 2023-01-10

On January 9, 2023, the European Food Safety Authority (EFSA) issued an opinion on the review of the existing maximum residue level of dithianon.

In accordance with Chapter 12 of Commission Regulation 396/2005, the EFSA has reviewed the maximum residue limits for thienonum. Based on the evaluation of the available data, MRL proposals were made and consumer risk assessments were conducted. While no apparent risk to consumers was identified, some of the information required by the regulatory framework was missing. In particular, it is emphasized that the toxicological reference values for metabolite 1,4-naphthoquinone are only provisional and are subject to conclusions on potential mutagenicity. As such, consumer risk assessments are only considered indicative and some of the MRL recommendations made by EFSA still require further consideration by risk managers. Some of the original articles are reported below:

According to Article 12 of Regulation (EC) No 396/2005, EFSA has reviewed the maximum residue levels (MRLs) currently established at European level for the pesticide dithianon. To assess the occurrence of dithianon residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Commission Regulation (EC) No 33/2008, the MRLs established by the Codex Alimentarius Commission as well as the European authorisations reported by Member States and the UK, including the supporting residues data. Given that a data gap as regards the magnitude of residues of the metabolites 1,4-naphthoquinone and phthalic acid was identified in the peer review for dithianon in light of co nfirmatory data, the toxicological profile of these metabolites was also assessed in the framework of the Article 12 MRL review. based on the assessment of the available data, MRL proposals were derived and a consumer risk assessment was carried out. Although no apparent risk to consumers was identified, some information required by the regulatory f ramework was missing. In particular, it is highlighted that the toxicological reference values derived for the metabolite 1,4-naphthoquinone are provisional only, pending a co nclusion on the mutagenicity potential. Hence, the consumer risk assessment is considered indicative only and some MRL proposals derived by EFSA still require further co nsideration by risk managers.

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