What Are The Drugs To Improve Memory Loss?

Whether memory loss can be recovered or not isrelated to its causes. Some causes of memory loss are reversible, such asstress, depression, anxiety, overuse of the brain, physical fatigue, orlong-term chronic malnutrition. These reasons are usually in the Aftercorrection, such as by adjusting the law of life, ensuring adequate nutrition,regular work and rest time, after a period of adjustment, the memory declinecan be recovered. However, memory loss caused by some diseases may be moredifficult to recover. Common diseases that cause brain lesions such as braintumors, severe brain trauma, cerebral apoplexy, cerebral hemorrhage orencephalitis, etc. In addition, chronic neurodegenerative diseases such asParkinson's disease, senile dementia, etc., the memory loss caused by thesediseases is usually difficult to reverse due to pathological factors.Therefore, memory loss caused by disease is usually more difficult to recover.To reduce memory loss, we must first identify the cause of memory loss, andthen symptomatic treatment can be effective.

First, for memory loss caused by Alzheimer'sdisease, cholinesterase inhibitors can be used. Cholinesterase inhibitors are aclass of drugs that can combine with cholinesterase (ChE) and inhibit theactivity of ChE. Its function is to accumulate Ach released from cholinergicnerve endings, showing enhanced M-like and N-like effects. Play the role ofexciting cholinergic receptors, so this class of drugs is also called cholinergicdrugs. This drug is mostly used clinically with donepezil, which can passthrough the blood-brain barrier and inhibit the hydrolysis of acetylcholine inthe brain, and it is one of the effective drugs to improve memory loss in theelderly. However, long-term overdose can cause nausea, vomiting, abdominalpain, sweating, increased saliva, muscle tremors and aggravation of muscleweakness. In severe cases, the patient is abnormally weak and fatigued, themuscles of the upper limbs, neck, shoulders, tongue, etc. are paralyzed, andthe language is unclear. Unsteady gait, convulsions or clonus, and even coma.For moderate and severe senile dementia, glutamate receptor antagonists canalso be used for treatment. Glutamate receptor antagonists are a class of agentsthat antagonize the activity of glutamate receptors. Reduce the toxic effectscaused by excessive glutamatergic excitation, and can affect the normallearning and memory functions mediated by glutamatergic. At present, memantineis commonly used drugs to improve memory loss in the market, which can helpblock neuronal damage caused by the pathological increase of glutamateconcentration. According to research, memantine can improve the cognitivefunction of some patients, which can increase the patients' language ability,improve their mood, and increase their sense of pleasure. When Alzheimer'spatients are in the middle and late stages, they are often in a bad mood, andthey are irritable and irritable. Taking this medicine can improve the symptomsin this area. Common adverse reactions (incidence less than 2%) of memantineare hallucinations, confusion, dizziness, headache, and fatigue. Rare adversereactions (incidence 0.1-1%) were anxiety, increased muscle tone, vomiting,cystitis, and increased libido.

Second, if the memory loss is due to vasculardementia, in addition to cholinesterase inhibitors, antiplatelet drugs aremainly used to improve circulation, and statins are used to reduce cerebralischemia. Antiplatelet drugs, also known as platelet inhibitors, have thefunctions of inhibiting platelet adhesion and aggregation and releasing andinhibiting thrombosis. Aspirin is the most widely used drugs to improve memoryloss in clinical practice. It is mainly used in small doses for coronaryatherosclerotic heart disease, myocardial infarction, cerebral infarction andsome deep vein thrombosis and pulmonary infarction. As adjunctiveantithrombotic therapy to thrombolytic therapy, there are also prostanol,dipyridamole, cilostazol. Statins, namely 3-hydroxy-3-methylglutaryl coenzyme A(HMG-CoA) reductase Inhibitors can not only potently reduce total cholesteroland low-density lipoprotein, but also reduce triacylglycerol to a certainextent and increase high-density lipoprotein, so statins drugs can also becalled more comprehensive drugs to improve memory loss. In recent years,studies have found that statins have a variety of non-lipid-lowering effects,including inhibition of atherosclerosis and thrombosis, relief of rejectionreaction after organ transplantation, treatment of osteoporosis, anti-tumor,anti-alzheimer's disease and other effects. At the same time, patients shouldbe treated with symptomatic support, such as malnutrition, lung infection,urinary tract infection, pressure ulcers, etc., in dementia patients,gastrointestinal nutrition supplements and anti-infection drugs should be givenaccordingly. In addition, we must pay attention to cognitive rehabilitationtraining.

There are many reasons for memory loss. Inaddition to drugs to improve memory loss, patients should also pay moreattention to participating in and exercising more, communicating with othersmore, and doing more brain-building activities in their daily life. In terms ofnutrition, it is necessary to supplement more high-quality protein, traceelements and vitamins. It is recommended that patients eat more foods that havebrain-boosting effects such as walnuts and black sesame seeds.