Direct or indirect trauma to the neck or cervical spine may cause damage to the intima of the internal carotid artery or vertebral artery, on which inflammation and bleeding may occur, leading to local thrombosis and spreading distally, causing cerebral infarction of the corresponding blood supply. Post-traumatic occlusion of the internal carotid artery may spread upward to involve the ophthalmic artery, anterior choroidal artery, the anterior part of the Willis circle, and even the anterior and middle cerebral arteries. In mild cases, localized neurological dysfunction may occur, while in severe cases, large cerebral infarction and deep coma may occur, with one-third of patients often being life-threatening.