Second-generation cephalosporin antibiotics, hydrolyzed into cefuroxime after entering the body. It has strong antibacterial effects on most Gram-positive cocci, and has good effects on diphtheria and Gram-positive anaerobic bacteria; it has strong activity against Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae, and Haemophilus influenzae; it is also very sensitive to Salmonella typhi, Shigella, Neisseria gonorrhoeae, and Neisseria meningitidis; it has poor antibacterial effects on Bacteroides fragilis; it is resistant to Serratia, Alcaligenes, Acinetobacter, and Pseudomonas aeruginosa. The mechanism of action is to bind to penicillin-binding proteins (PBPs) on the bacterial cell membrane, inhibit the synthesis of bacterial septum and cell wall, and cause the bacteria to dissolve and die.

Second-generation cephalosporin antibiotics are rapidly hydrolyzed into cefadroxil after entering the body. They have strong antibacterial effects on most Gram-positive cocci, good effects on diphtheria and Gram-positive anaerobic bacteria, strong activity on Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae and Haemophilus influenzae, sensitive to some Enterobacter aerogenes, indole-positive Proteus and Providencia, sensitive to Salmonella typhi, Shigella, Neisseria gonorrhoeae and Neisseria meningitidis, poor effect on Bacteroides fragilis, and resistance to Serratia, Alcaligenes, Acinetobacter and Pseudomonas aeruginosa. The mechanism of action is to bind to penicillin-binding proteins (PBPs) on the bacterial cell membrane, inhibit the synthesis of bacterial septum and cell wall, inhibit cell division and growth, and ultimately lead to bacterial lysis and death.

It has good antibacterial effect on Escherichia coli, Klebsiella, Proteus, Salmonella typhi, Shigella, Citrobacter and other Enterobacteriaceae and Pseudomonas aeruginosa. Haemophilus influenzae, Neisseria gonorrhoeae and Neisseria meningitidis are highly sensitive to it. It also has good effect on various groups of streptococci and pneumococci, and only has moderate effect on Staphylococcus aureus (methicillin-sensitive strain). It has good effect on most Gram-positive anaerobes and some Gram-negative anaerobes. It mainly inhibits the synthesis of bacterial cell walls.

It has a weak antibacterial effect itself and is a competitive, irreversible β-lactamase inhibitor. When used in combination with cefoperazone, it can increase the ability of cefoperazone to resist degradation by multiple β-lactamases and produce a significant synergistic effect on cefoperazone.