This product belongs to the macrolide antibiotics, which is the ethyl succinate of erythromycin. It is more stable than erythromycin in gastric acid. It has antibacterial activity against Staphylococcus (except methicillin-resistant strains), various groups of streptococci and Gram-positive bacilli. Neisseria, Haemophilus influenzae, Bordetella pertussis, etc. are also sensitive to this product. This product also has antibacterial effects on various anaerobic bacteria except Bacteroides fragilis and Fusobacterium. It also has inhibitory effects on Legionella, Campylobacter fetus, some spirochetes, Mycoplasma pneumoniae, Rickettsia and Chlamydia. This product is an antibacterial agent, but it also has a bactericidal effect on some bacteria at high concentrations. This product can penetrate the bacterial cell membrane and form a reversible bond with the 50S subunit of the bacterial ribosome near the donor site (P site), blocking the transfer RNA (t-RNA) from binding to the P site, and also blocking the displacement of the polypeptide chain from the acceptor site (A site) to the P site, thereby inhibiting bacterial protein synthesis.

This product acts specifically on the gastric mucosal parietal cells, reducing the activity of H/KATPase in the parietal cells, thereby inhibiting the secretion of gastric acid. Compared with omeprazole and lansoprazole, this product has a weaker inhibitory effect on cytochrome P450-dependent enzymes. No adverse effects were found in either short-term or long-term administration of pantoprazole. This drug is non-carcinogenic, does not impair fertility, and does not induce teratogenesis. After 2.5 years of continuous medication, there were no changes in various experimental parameters of liver enzymology and cholesterol metabolism.

This product is a mucus regulator, which mainly acts on the secretion of bronchial glands, increasing the secretion of low-viscosity salivary mucin and reducing the production of high-viscosity fucoxomucin, thereby reducing the viscosity of sputum and making it easier to cough up. It takes effect quickly after oral administration, and obvious therapeutic effects can be seen within 4 hours of taking it.

1. It has a strong antipyretic effect on rabbits with fever caused by bacterial endotoxins, can promote the disappearance of fever, and the effect is rapid and can last for more than 4 hours; 2. It can counteract the increased permeability of capillary walls caused by xylene or histamine; 3. It can shorten the sleep latency of mice caused by sodium pentobarbital, prolong their sleep time, and can also enhance the subthreshold effect of sodium pentobarbital to induce sleep in mice, indicating a significant sedative effect; 4. It can significantly promote the adrenal cortex function of rats and increase the body's emergency response to pathogen infection; 5. It has a certain inactivation effect on influenza virus type AⅠ, type AⅢ, pneumonia adenovirus (Adv) type III, type IV, and enterosyncytial virus (Rsv) in vitro.

This product is a potassium sodium salt of dehydrated andrographolide succinate half ester made by esterification, dehydration and salt formation of andrographolide extract from the plant Andrographis paniculata. It is the same substance as the active metabolite of Andrographolide in the body. It has the effects of antipyretic, anti-inflammatory, sedative, enhancing adrenal cortex function and inactivating multiple viruses in vitro.