By acting on the smooth muscle of the coronary and peripheral blood vessels and the atrioventricular node, inhibiting the influx of Ca2 into the cells, it exhibits vasodilation and prolongs the conduction time of the atrioventricular node, thus being effective for hypertension, arrhythmia, and angina pectoris. 1. Effect on blood pressure: 1) It can reduce hypertension under anesthesia and without anesthesia, but the effect is stronger under anesthesia than without anesthesia, and it has a stronger antihypertensive effect on blood pressure higher than normal blood pressure (rat). 2) While reducing blood pressure, it reduces peripheral vascular resistance and myocardial oxygen consumption, and increases cardiac output (dog). 3) It lowers blood pressure without reducing blood flow to the brain, coronary arteries, and kidneys. It also exhibits a sodium diuretic effect (dog, monkey). 2. Effect on arrhythmia: 1) It prolongs the conduction time, effective refractory period, and functional refractory period of the atrioventricular node, and exhibits an effect on supraventricular tachyarrhythmia (dog). 2) It inhibits supraventricular tachyarrhythmia caused by atrial electrical stimulation (rabbit). 3. Effects on myocardial ischemia: 1) Improve the balance of myocardial oxygen supply and demand ① Dilate the main coronary artery and side branches, increase blood flow to the ischemic part of the myocardium (dogs). ② Inhibit coronary artery spasm (pigs, humans). 2) Myocardial protection When myocardial ischemia occurs, it inhibits excessive influx of Ca2 into cells, maintains cardiac function and myocardial energy metabolism, and reduces the infarct focus (dogs, cats).

It achieves bactericidal effect by inhibiting the synthesis of bacterial cell wall. It has bactericidal effect on a wide range of common clinical bacteria and can resist hydrolysis by a variety of beta-lactamases. Bacteria sensitive to this product include Gram-positive bacteria, Gram-negative bacteria and some anaerobic bacteria.

It achieves bactericidal effect by inhibiting the synthesis of bacterial cell wall. It has bactericidal effect on a wide range of common clinical bacteria and can resist hydrolysis by a variety of beta-lactamases. Bacteria sensitive to this product include Gram-positive bacteria, Gram-negative bacteria and some anaerobic bacteria.

It achieves bactericidal effect by inhibiting the synthesis of bacterial cell wall. It has bactericidal effect on a wide range of common clinical bacteria and can resist hydrolysis by a variety of beta-lactamases. Bacteria sensitive to this product include Gram-positive bacteria, Gram-negative bacteria and some anaerobic bacteria.

This product is a third-generation cephalosporin antibiotic. It has high antibacterial activity against Escherichia coli, Klebsiella pneumoniae and other Enterobacteriaceae, Haemophilus influenzae, Pseudomonas aeruginosa, etc. It also has good antibacterial effects on nitrate-negative bacilli, Alcaligenes, etc. Most beta-lactamases produced by bacteria are highly stable, so it can still have antibacterial activity against multi-drug resistant strains of most of the above-mentioned Gram-negative bacilli. Gram-positive cocci such as pneumococci and hemolytic streptococci are highly sensitive to this product, but this product has only moderate activity against staphylococci, while enterococci and methicillin-resistant Staphylococci are often resistant to this product. This product has certain antibacterial activity against anaerobic bacteria such as Peptococcus and Peptostreptococci, but has poor antibacterial effect against Bacteroides fragilis. Its mechanism of action is to bind to penicillin-binding proteins (PBPs) on the bacterial cell membrane, acylate the transpeptidase, inhibit the synthesis of the bacterial septum and cell wall, affect the cross-linking of the cell wall mucopeptide components, inhibit cell division and growth, elongate the bacterial morphology, and finally dissolve and die.