It combines with pyrophosphate in the body to form a coenzyme, participates in the oxidative decarboxylation reaction of pyruvate and α-ketoglutarate in sugar metabolism, and is necessary for sugar metabolism. When it is deficient, oxidation is blocked to form pyruvate and lactic acid accumulation, which affects the body's energy supply and may cause symptoms of the nervous and cardiovascular systems, including multiple peripheral neuritis (paresthesia, neuralgia, limb weakness, muscle aches and atrophy), cardiovascular manifestations such as palpitations, shortness of breath, chest tightness, cardiac hypertrophy, liver and lung congestion and peripheral edema, and digestive tract manifestations such as decreased appetite leading to weakness and weight loss.

This product is a glucocorticoid with anti-inflammatory, immunosuppressive, antitoxin and anti-shock effects. (1) Anti-inflammatory effect: It has an effect on inflammation caused by various causes except viruses. Glucocorticoids reduce and prevent tissue response to inflammation, thereby reducing the symptoms of inflammation. They can also inhibit the repair of tissues in the later stages of inflammation and reduce sequelae. (2) Immunosuppressive effect: It prevents or inhibits cell-mediated immune responses, delayed allergic reactions, and reduces the expansion of primary immune responses. (3) Anti-toxic and anti-shock effects: Glucocorticoids can improve the body's tolerance, reduce cell damage, and play a role in protecting the body. It also has the effects of dilating blood vessels, enhancing myocardial contractility, and improving microcirculation.

This product is an H2 receptor antagonist, which can significantly inhibit the basal and nocturnal gastric acid secretion of normal people and ulcer patients, as well as the gastric acid secretion caused by pentagastrin, histamine and meals, and has a certain inhibitory effect on the secretion of pepsinogen. It has a protective effect on experimental gastric mucosal damage and acute ulcers. It has no effect on the secretion of gastrin and sex hormones.

1. Effect on water and electrolyte excretion: It can increase the excretion of water, sodium, chloride, potassium, calcium, magnesium, phosphorus, etc.; mainly by inhibiting the active reabsorption of NaCl by the thick wall segment of the renal tubular loop, reducing the osmotic pressure gradient difference of the medullary interstitial fluid, reducing the reabsorption of water, Na+, and Cl-, promoting the excretion of K+ and H+, and may inhibit the reabsorption of Na+ and Cl- by the proximal and distal tubules, and promote the secretion of K+ by the distal tubules; short-term medication increases uric acid excretion, and long-term medication can cause hyperuricemia. 2. Effect on hemodynamics: Furosemide can inhibit the activity of prostaglandin degrading enzymes, increase the content of prostaglandin E2, dilate blood vessels, increase renal blood flow, and reduce renal vascular resistance; while diuresis, it does not reduce the glomerular filtration rate; it can also dilate the pulmonary capacitance veins, reduce the permeability of pulmonary capillaries, reduce the amount of blood returning to the heart, and reduce the left ventricular end-diastolic pressure, which is helpful for the treatment of acute left heart failure and adult respiratory distress syndrome.