Jinhua Enterprise (Group) Co., Ltd. Xi'an Jinhua Pharmaceutical Factory

It has an inhibitory effect on a variety of Gram-positive and Gram-negative bacteria in vitro, and has a stronger inhibitory effect on hemolytic Streptococcus, Staphylococcus aureus, Vibrio cholerae, Neisseria meningitidis, Shigella, Salmonella typhi, Corynebacterium diphtheriae, etc. It also has a certain inhibitory effect on amoeba.

It mainly interferes with bacterial folate metabolism, selectively inhibits dihydrofolate reductase, and prevents nucleic acid synthesis.

Inhibits prostaglandin synthesis and has antipyretic and analgesic effects

Inhibits prostaglandin synthesis and has antipyretic and analgesic effects

Central nervous system stimulants that can enhance the antipyretic and analgesic effects of the above drugs

Inhibits the influx of Na+ and Ca2+ ions across the cell membrane, and stabilizes the cell membrane of excitable cells such as bronchial smooth muscle and inflammatory cells

Blocks bronchial smooth muscle choline M receptors and histamine H1 receptors, relaxes bronchial smooth muscle, inhibits the release of allergic mediators, and reduces capillary permeability

Stimulate beta 2 receptors, promote the release of norepinephrine from nerve endings, enhance diaphragmatic contraction, and help improve respiratory function; stimulate alpha receptors on airway vascular smooth muscle, constrict airway blood vessels, and inhibit congestion and edema

No specific mention of pharmacological effects

It reduces viscosity by changing mucin synthesis, promotes airway ciliary movement, and enhances diaphragmatic contraction.

No specific mention of pharmacological effects

Blocks bronchial smooth muscle cholinergic M receptors, relaxes bronchial smooth muscle

It has central and peripheral antitussive effects, and its antitussive strength is 1/3 of codeine. In addition to having a direct inhibitory effect on the respiratory center of the medulla oblongata, it also has a mild atropine-like effect, which can relax spasmodic bronchial smooth muscles and reduce airway resistance.

It can reflexively increase the secretion of respiratory mucosal glands, making it easier to discharge sputum and facilitating the removal of sticky sputum.

It is a sulfonamide antibiotic that acts on dihydrofolate synthase. When used in combination with trimethoprim, it can double block bacterial folate metabolism and enhance the synergistic antibacterial effect, especially against Escherichia coli, Haemophilus influenzae, Staphylococcus aureus, etc.

It is a sulfonamide synergist that acts on dihydrofolate reductase. When used in combination with sulfamethoxazole, it can double block bacterial folate metabolism, enhance synergistic antibacterial effects, and reduce the emergence of drug-resistant strains.