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This product belongs to Class III antiarrhythmic drugs. The main electrophysiological effect is to prolong the action potential and effective refractory period of various myocardial tissues, which is conducive to eliminating reentrant excitation. At the same time, it has mild non-competitive α and β adrenergic receptor blocking and mild Class I and IV antiarrhythmic properties. Reduce the automaticity of the sinus node. It has no effect on the resting membrane potential and action potential height. The inhibition of forward conduction of the atrioventricular bypass pathway is greater than the reverse. Due to excessive prolongation of repolarization, the electrocardiogram has QT interval prolongation and T wave changes after oral administration, which can slow down the heart rate by 15~20% and prolong the PR and Q-T intervals by about 10%. It has a direct dilation effect on the coronary arteries and peripheral blood vessels. It can affect thyroid hormone metabolism. The characteristics of this product are long half-life, so the number of medications is small, the therapeutic index is large, and the antiarrhythmic spectrum is wide.

This product can neutralize gastric acid and protect the gastric mucosa with a long-lasting effect.

This product can neutralize gastric acid and protect the gastric mucosa with a long-lasting effect.

This product can neutralize gastric acid and protect the gastric mucosa with a long-lasting effect.

The main pharmacological action is to relax vascular smooth muscle. Nitroglycerin releases nitric oxide (NO), which is the same as endothelial relaxing factor, activating guanylate cyclase, increasing cyclic guanosine monophosphate (cGMP) in smooth muscle and other tissues, leading to dephosphorylation of myosin light chain, regulating the contractile state of smooth muscle, and causing vasodilation.

Activation inhibits the release of pain transmitters from the lateral cord, leading to hyperactivation of intrinsic factor, which binds to the U subtype opioid receptors and inhibits serotonin and norepinephrine, thereby eliminating the pain response.