This product is a potassium sodium salt of dehydrated andrographolide succinate half ester made by esterification, dehydration and salt formation of andrographolide extract from the plant Andrographis paniculata. It is the same substance as the active metabolite of Andrographolide in the body. It has the effects of antipyretic, anti-inflammatory, sedative, enhancing adrenal cortex function and inactivating multiple viruses in vitro.

This product has a broad-spectrum antibacterial effect, especially high antibacterial activity against aerobic Gram-negative rods, and has good antibacterial activity against the following bacteria in vitro: 1. Most bacteria of the Enterobacteriaceae family, including Citrobacter, Enterobacter cloacae, Enterobacter aerogenes, Escherichia coli, Klebsiella, Proteus, Salmonella, Shigella, Vibrio, Yersinia, etc. It also has high antibacterial activity against penicillin-resistant Neisseria gonorrhoeae, enzyme-producing Haemophilus influenzae, and Moraxella. 2. It has antibacterial activity against most strains of Pseudomonas, such as Pseudomonas aeruginosa. 3. It has antibacterial activity against methicillin-sensitive Staphylococcus aureus, and only moderate antibacterial activity against Streptococcus pneumoniae, hemolytic Streptococcus, and Enterococcus faecalis. It has good antimicrobial effects against Chlamydia trachomatis, Mycoplasma, and Legionella, and also has antibacterial activity against Mycobacterium tuberculosis and atypical mycobacteria. It has poor antibacterial activity against anaerobic bacteria. 4. Ofloxacin is a bactericide that acts on the A subunit of bacterial DNA helicase, inhibiting DNA synthesis and replication, leading to bacterial death. The drug resistance of this product is currently increasing, and there is cross-resistance with other quinolones.

Extract from the above information

Lomeza is a broad-spectrum quinolone antibiotic that has bactericidal effects on Gram-negative bacteria, Gram-positive bacteria and some anaerobic bacteria. It has good antibacterial effects on methicillin-resistant Staphylococcus aureus, ampicillin-resistant influenza bacilli, pipemidic acid-resistant Escherichia coli and bacteria resistant to other drugs. Its antibacterial mechanism is to inhibit the activity of bacterial DNA helicase, thereby inhibiting bacterial DNA transcription and replication, and has bactericidal effects on a variety of Gram-positive and Gram-negative bacteria.

It has a strong antipyretic effect on rabbits with fever caused by bacterial endotoxins; it can counteract the increased permeability of capillary walls caused by xylene or histamine; it has a significant sedative effect; it can significantly promote the adrenal cortex function of rats and enhance the body's emergency response to pathogen infection; it has a certain inactivation effect on influenza virus type A1, type A3, pneumonia adenovirus (Adv) type III, type IV, enterosyncytial virus and respiratory syncytial virus (RSV) in vitro.