This product is a semi-synthetic penicillin, which has good antibacterial effect on Gram-positive bacteria, Gram-negative bacteria and Pseudomonas aeruginosa. It can produce synergistic effect when used in combination with amikacin, gentamicin and netilmicin.

Extracting pharmacological effects from the above information

Cefoperazone is a third-generation cephalosporin that achieves its bactericidal effect by inhibiting the biosynthesis of sensitive bacterial cell walls. Since tazobactam can bind to certain penicillin-binding proteins, sensitive strains may be more sensitive to this compound preparation than to cefoperazone alone.

Tazobactam has no antibacterial activity against other bacteria except Neisseriaceae and Acinetobacter. However, tazobactam has an irreversible inhibitory effect on most important β-lactamases produced by β-lactam antibiotic-resistant strains. Therefore, tazobactam can prevent the destruction of penicillins and cephalosporins by related resistant bacteria, reflecting that tazobactam has a certain synergistic effect with penicillins and cephalosporins.