Suicheng Pharmaceutical Co., Ltd.

It has the effects of anti-platelet aggregation, dilating arterioles, improving microcirculation, activating blood circulation and removing blood stasis, and has the effect of disaggregating aggregated platelets

This product is a H2 receptor blocker of the guanyl thiazole class, which has the characteristics of high affinity for H2 receptors, and has a significant inhibitory effect on gastric acid secretion, and has an inhibitory effect on basal secretion and the increase of gastric acid and pepsin caused by various stimuli. This product does not change the gastric emptying rate, does not interfere with pancreatic function, and has no adverse effects on the cardiovascular system and kidney function. This product is different from cimetidine, but it is similar to ranitidine, that is, long-term high-dose treatment does not cause adverse reactions of androgen antagonism such as male breast development, impotence, lack of sexual desire, and female breast pain, galactorrhea, etc. It has no teratogenic, carcinogenic, drug enzyme inhibitory and androgen inhibitory effects.

It is an oxidized derivative of adrenaline and has no adrenaline-mimetic effect, so it does not affect blood pressure and heart rate, but it can enhance the resistance of capillaries to damage, stabilize the acidic mucopolysaccharides in blood vessels and surrounding tissues, reduce the permeability of capillaries, and enhance the retraction effect of damaged capillary ends, making it difficult for blood clots to fall off the tube wall, thereby shortening the hemostasis time, but it does not affect the coagulation process.

Its antiasthmatic effect is similar to that of theophylline, and its cardiac stimulant effect is only 1/20 to 1/10 of that of aminophylline. It has less effect on the heart and nervous system and is suitable for asthma patients with tachycardia. It has a direct relaxant effect on the smooth muscles of the respiratory tract, and may increase the intracellular cAMP content by inhibiting phosphodiesterase, or produce a bronchial dilation effect by releasing endogenous adrenaline and noradrenaline. At the same time, as a purine receptor blocker, it can counteract the contractile effect of adenine on the respiratory tract, and can also enhance the contractility of the diaphragm to improve respiratory function.

It is a vasodilator that can dilate coronary arteries and cerebral blood vessels, reduce myocardial oxygen consumption, improve microcirculation and resist platelet aggregation. Animal experiments have shown that: 1. The various total flavonoid compounds in Pueraria root can relax smooth muscles, while the contractile components may be substances such as choline, acetylcholine and carbazine R; 2. Pueraria root has a certain antihypertensive effect on normal and hypertensive animals; 3. Pueraria root total flavonoids and puerarin have a significant dilating effect on coronary arteries, which can dilate normal and spasmodic coronary arteries. After intravenous injection of 30mg/Kg, coronary blood flow can increase by 40% and vascular resistance can decrease by 29%; 4. Puerarin can also inhibit the release of 5-HT in platelets induced by thrombin.