Thyroid tablets
Function and Efficacy
This product is a thyroid hormone drug. The main ingredients of this product are thyroid hormones including thyroxine (T4) and triiodothyronine (T3). It has the function of promoting catabolism (heat-raising effect) and anabolism, and has an important influence on the normal metabolism and growth and development of the human body. It is very important for the development of the central nervous system of infants and young children. The basic function of thyroid hormone is to induce the synthesis of new proteins including special enzyme systems, and regulate the metabolism of three major substances: protein, carbohydrates and fats, as well as water, salt and vitamins. Because thyroid hormones induce the synthesis of cell membrane Na-K pumps and enhance their activity, energy metabolism is enhanced. Thyroid hormones (mainly T3) bind to specific receptors in the nucleus, and the latter undergo conformational changes to form dimers. The activated receptors bind to specific receptors on DNA.
Ingredients
The main ingredient of this product is thyroid powder, which is taken from edible animals such as pigs, cattle, and sheep.
Appearance
This product is a white sugar-coated tablet, which appears light yellow to light brown after removing the sugar coating; it has a slight peculiar odor.
Indication
Used for hypothyroidism caused by various reasons.
Usage and Dosage
1. Common dosage for adults: oral administration, starting with 10-20 mg per day, gradually increasing, maintenance dose is generally 40-120 mg per day, a few patients need 160 mg per day. 2. Complete replacement dose for infants and children: 8-15 mg for children under 1 year old; 20-45 mg for 1-2 years old; 45-60 mg for 2-7 years old; 60-120 mg for children over 7 years old. The initial dose should be 1/3 of the complete replacement dose, and the dose should be increased gradually. Since the content of T3 and T4 in this product and the ratio of the two are not constant, the dose should be adjusted according to clinical symptoms and T3, T4, and TSH examinations during treatment.
Adverse Reactions
Thyroid tablets have no adverse reactions if used in appropriate dosage. Overdose may cause tachycardia, palpitations, angina, arrhythmia, headache, nervousness, excitement, restlessness, insomnia, skeletal muscle spasms, muscle weakness, tremor, sweating, flushing, heat intolerance, diarrhea, vomiting, weight loss and other symptoms similar to hyperthyroidism. All symptoms can be eliminated by reducing the dosage or stopping the drug.
Precautions
It is contraindicated for patients with angina pectoris, coronary heart disease and tachyarrhythmia.
Special Population Medication
Precautions for children: This test has not been conducted and there are no reliable references. Precautions for pregnancy and lactation: It can cause thyroid dysfunction in the fetus and infant, so pregnant and lactating women should use it with caution. Precautions for the elderly: Elderly patients are more sensitive to thyroid hormones. The amount of thyroid hormone replacement required for those over 60 years old is about 25% lower than that of young people. In addition, elderly patients have poor cardiovascular function and should use it with caution.
Drug Interactions
1. Diabetic patients taking thyroid hormones should appropriately increase the dose of insulin or hypoglycemic drugs depending on blood sugar levels. 2. When thyroid hormones are used in combination with anticoagulants such as dicoumarol, the latter's anticoagulant effect is enhanced, which may cause bleeding; the dose of anticoagulants should be adjusted according to the prothrombin time. 3. When this type of drug is used in combination with tricyclic antidepressants, the effects and toxic side effects of both types of drugs are enhanced, so attention should be paid to adjusting the dose. 4. For those taking estrogen or contraceptives, the dose of thyroid hormone should be appropriately adjusted when used in combination because the level of thyroxine-binding globulin in the blood increases. 5. Cholestyramine or cholestipol can weaken the effect of thyroid hormones. When the two types of drugs are used together, they should be taken 4 to 5 hours apart, and thyroid function should be measured regularly. 6. β-adrenergic receptor blockers can reduce the conversion of T4 to T3 in peripheral tissues, so attention should be paid when used in combination.
Storage
Keep in a dark place (no more than 30℃) and store in a sealed container.
Packaging Specification
40mg
Validity Period
24 months
Manufacturer
Liaocheng Zhongtai Pharmaceutical Company
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Founded in:
2002-04-30 -
Address:
No. 3, Liaolin East Road, Jiaming Economic Development Zone, Liaocheng -
Tax NO.:
913715007433941785 -
Registered Funds:
50 million yuan -
Website:
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Email: