Equine Tetanus Immunoglobulin (F(ab)2)

Not yet clear.

A liquid antitoxin globulin preparation made from plasma obtained from horses immunized with tetanus toxoid, which is purified after gastric enzyme digestion.

Used to prevent and treat tetanus. When tetanus or suspected symptoms have appeared, antitoxin treatment should be used in time while undergoing surgical treatment and other therapies. When there is a risk of tetanus infection from open wounds (especially those with deep wounds and serious contamination), prevention should be carried out in time. Anyone who has received tetanus toxoid immunization should receive another injection of toxoid to strengthen immunization after the injury, and there is no need to inject antitoxin; those who have not received toxoid immunization or have an unclear immunization history must be injected with antitoxin for prevention, but should also start toxin-like preventive injections at the same time to obtain lasting immunity.

Usage: Subcutaneous injection should be made at the attachment of the deltoid muscle of the upper arm. When injecting toxoids at the same time, the injection sites must be separated. Intramuscular injection should be made in the middle of the deltoid muscle of the upper arm or the outer upper part of the gluteus maximus. Intravenous injection can only be performed if no abnormal reaction occurs after subcutaneous or intramuscular injection. Intravenous injection should be slow, not exceeding 1 ml per minute at the beginning, and not exceeding 4 ml per minute thereafter. A single intravenous injection should not exceed 40 ml, and children should not exceed 0.8 ml per 1 kg of body weight. The antitoxin can also be added to glucose injection, sodium chloride injection and other infusions for intravenous drip. Before intravenous injection, heat the vial in warm water to close to body temperature. If an abnormal reaction occurs during the injection, stop immediately. Dosage: 1. Prevention: 1500-3000 IU subcutaneously or intramuscularly once, for children and adults

1. Anaphylactic shock: It may occur suddenly during the injection or within a few minutes to tens of minutes after the injection. The patient suddenly shows depression or irritability, pale or flushed face, chest tightness or shortness of breath, cold sweat, nausea or abdominal pain, rapid pulse, decreased blood pressure, and in severe cases, coma or collapse. If not rescued in time, death may occur quickly. Mild cases can be relieved after injection of epinephrine: severe cases require infusion of oxygen, use of pressor drugs to maintain blood pressure, and use of anti-allergic drugs and adrenal cortex hormones for rescue. 2. Serum sickness: The main symptoms are urticaria, fever, swollen lymph nodes, local edema, and occasionally proteinuria, vomiting, joint pain, erythema, itching and edema at the injection site. Generally, the onset is 7 to 14 days after the injection, which is called the delayed type. There are also cases in which the onset is 2 to 4 days after the injection, which is called the accelerated type.

Use with caution in patients with positive allergy test. See desensitization injection method for details.

Not yet clear.

Store and transport at 2-8°C away from light.

100 million units

36 months.

Shanghai Serum Bio-Technology Co., Ltd.

• Founded in:

  1999-11-09

• Address:

  No. 1288, Huaqing Road, Qingpu District, Shanghai

• Tax NO.:

  91310000631521822M

• Registered Funds:

  108.22 million yuan

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