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Famotidine for injection

Function and Efficacy

This product is a H2 receptor antagonist of the guanyl thiazole class, which has the characteristics of high affinity for H2 receptors, and has a significant inhibitory effect on gastric acid secretion, and has an inhibitory effect on basal secretion and the increase of gastric acid and pepsin caused by various stimuli. This product does not change the gastric emptying rate, does not interfere with pancreatic function, and has no adverse effects on the cardiovascular system and kidney function. This product is different from cimetidine, but it is similar to ranitidine, that is, long-term high-dose treatment does not cause androgen antagonism side effects such as male breast development, impotence, lack of libido, and female breast pain and galactorrhea, etc. It has no teratogenic, carcinogenic, drug enzyme inhibitory and androgen inhibitory effects.

Ingredients

The main ingredient of this product is famotidine. Its chemical name is 3-[[[2-[(diaminomethylene)amino]-4-thiazolyl]methyl]thio]-N-sulfamoylpropionamidine. Molecular formula: C8H15N7O2S3, molecular weight: 337.45.

Name Description Content CAS NO. Manufacturer
FamotidineIngredients

This product is a H2 receptor antagonist of the guanyl thiazole class, which has the characteristics of high affinity for H2 receptors, and has a significant inhibitory effect on gastric acid secretion, and has an inhibitory effect on basal secretion and the increase of gastric acid and pepsin caused by various stimuli. This product does not change the gastric emptying rate, does not interfere with pancreatic function, and has no adverse effects on the cardiovascular system and kidney function. This product is different from cimetidine, but it is similar to ranitidine, that is, long-term high-dose treatment does not cause androgen antagonism side effects such as male breast development, impotence, lack of libido, and female breast pain and galactorrhea, etc. It has no teratogenic, carcinogenic, drug enzyme inhibitory and androgen inhibitory effects.

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76824-35-6 69

Appearance

This product is a white freeze-dried solid.

Indication

Bleeding peptic ulcer; acute gastric mucosal damage during stress, and gastrointestinal bleeding caused by nonsteroidal anti-inflammatory drugs.

Usage and Dosage

1 Adults: intravenous injection: 20 mg once, twice a day, dissolve in 20 ml of 0.9% sodium chloride injection or glucose injection, slowly inject intravenously or mix with infusion for intravenous drip. Intramuscular injection: 20 mg once, twice a day, dissolve in 1-1.5 ml of injection water, and inject intramuscularly. 2 Children: The dosage is generally 0.4 mg/kg once, twice a day, and the usage is the same as above.

Adverse Reactions

A small number of patients may experience dry mouth, dizziness, insomnia, constipation, diarrhea, rash, facial flushing, increased blood pressure, menstrual disorders, leukopenia, and occasionally mild increase in transaminase.

Precautions

It is contraindicated for those who are allergic to this product.

Special Population Medication

Precautions for children: Use with caution in infants and young children. Precautions for pregnancy and lactation: Use with caution in pregnant women; breastfeeding women should stop breastfeeding when using. Precautions for the elderly: Not yet clear.

Drug Interactions

This product does not interact with liver cytochrome P450 enzymes, so it does not affect the metabolism of other drugs.

Storage

Keep away from light and sealed. Valid for two years.

Packaging Specification

20mg

Validity Period

24 months

Manufacturer

Harbin Pharmaceutical Group Bioengineering Co., Ltd.

  • Founded in:

    1995-02-20
  • Address:

    No. 99, Zhuhai Road, Limin Development Zone, Hulan District, Harbin
  • Tax NO.:

    91230111128024298B
  • Registered Funds:

    186.0655 million yuan
  • Website:

  • Email:

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