Monosialotetrahexosylganglioside sodium injection

GM1 can promote the recovery of neurological function after central nervous system damage caused by various reasons. The mechanism of action is to promote neuroplasticity (including the survival of nerve cells, axon growth and synapse formation). GM1 has a protective effect on secondary neurodegeneration after injury. The application of GM1 has a good effect on the improvement of cerebral hemodynamic parameters and the reduction of brain edema after injury. GM1 reduces nerve cell edema by improving the activity of cell membrane enzymes. Animal experiments show that GM1 can improve behavioral disorders caused by Parkinson's disease.

In addition to the main active ingredients, this product also contains the following excipients: disodium hydrogen phosphate, sodium dihydrogen phosphate, sodium chloride and water for injection.

This product is a transparent liquid.

Central nervous system diseases include cerebrospinal cord trauma, cerebrovascular accident, and Parkinson's disease.

20-40 mg per day, once or divided into several intramuscular injections or slow intravenous drips. In the acute stage of the disease (especially acute trauma): 100 mg per day, intravenous drip; after 2-3 weeks, change to a maintenance dose of 20-40 mg per day, generally for 6 weeks. Parkinson's disease: The first dose is 500-1000 mg, intravenous drip; from the second day onwards, 200 mg per day, subcutaneous, intramuscular or intravenous drip, generally for 18 weeks.

A small number of patients may experience a rash-like reaction and should be advised to stop the medication.

It is contraindicated for patients who have been confirmed to be allergic to this product or those with hereditary abnormalities of lipid metabolism (gangliosidosis).

Precautions for children: So far, no adverse reactions have been reported in children using this product. Precautions for pregnancy and lactation: According to literature, no adverse reactions have been observed in various animals using monosialotetrahexosylganglioside during pregnancy and lactation. Precautions for the elderly: So far, no adverse reactions have been reported in elderly patients using this product.

So far, no interaction between this product and other drugs has been found.

Store at room temperature 15-30℃, valid for 36 months.

2 ml: 20 mg

24 months.

Harbin Medical University Pharmaceutical Co., Ltd.

• Founded in:

  1998-04-08

• Address:

  Bohai Road, Central Area, Haping Road, Harbin Development Zone

• Tax NO.:

  91230199702953105L

• Registered Funds:

  56.9258 million yuan

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