Insulin injection

This product is a hypoglycemic drug. The main effect of insulin is to lower blood sugar, and it also affects protein and fat metabolism, including the following effects: 1. Inhibit liver glycogenolysis and gluconeogenesis, and reduce liver output of glucose; 2. Promote liver uptake of glucose and synthesis of liver glycogen; 3. Promote muscle and adipose tissue to take up glucose and amino acids, promote protein and fat synthesis and storage; 4. Promote the liver to produce very low density lipoprotein and activate lipoprotein lipase, promote the decomposition of very low density lipoprotein; 5. Inhibit the decomposition of fat and protein in fat and muscle, inhibit the production of ketone bodies and promote the use of ketone bodies by surrounding tissues.

Sterile aqueous solution of insulin (porcine or bovine). Each 100 ml may contain 1.4-1.6 g of glycine and 0.22 g of m-cresol.

This product is a colorless or almost colorless clear liquid.

Hormone drugs. They can lower blood sugar, correct sugar and other metabolic disorders caused by diabetes. They are used to treat severe diabetes.

Subcutaneous injection or intravenous drip, the dosage is determined according to the condition.

Allergic reaction, redness, swelling, itching, urticaria, angioedema at the injection site. Hypoglycemia reaction, sweating, palpitations, fatigue, and in severe cases, impaired consciousness, ataxia, tachycardia, and even coma. Insulin resistance, daily dose must be more than 200 units. Fat atrophy and fat hyperplasia at the injection site. Refractive disorders.

Contraindicated in patients allergic to insulin.

Precautions for children: Children are prone to hypoglycemia, and their blood sugar fluctuates widely. The dosage should be adjusted by 0.5 to 1 unit, and gradually increased or decreased. The dosage should be appropriately increased for adolescents, and then gradually decreased after puberty. Precautions for pregnancy and lactation: Pregnant women with diabetes have an increased insulin requirement during pregnancy, and a reduced requirement after delivery. If the diabetes found during pregnancy is gestational diabetes, insulin treatment should be terminated after delivery. Follow up their blood sugar, and then decide on treatment based on whether they have diabetes. Precautions for the elderly: The elderly are prone to hypoglycemia, and they need to pay special attention to the appropriate amount of diet and physical activity.

Glucocorticoids, adrenocorticotropic hormone, glucagon, estrogen, oral contraceptives, epinephrine, phenytoin sodium, thiazide diuretics, thyroxine, etc. can increase blood sugar concentration to varying degrees. The dose of these drugs or insulin should be adjusted when used together. Oral hypoglycemic drugs and insulin have a synergistic hypoglycemic effect. Anticoagulants, salicylates, sulfonamides and anti-tumor drugs such as methotrexate can compete with insulin and bind to plasma proteins, thereby increasing the level of free insulin in the blood. Non-steroidal anti-inflammatory analgesics can enhance the hypoglycemic effect of insulin. Beta-receptor blockers such as propranolol can prevent the reaction of adrenaline to increase blood sugar and interfere with the body's function of regulating blood sugar. Using them together with insulin can increase the risk of hypoglycemia, and can mask the symptoms of hypoglycemia and prolong the duration of hypoglycemia. When used together, the dose of insulin should be adjusted. Moderate to large amounts of alcohol can enhance the hypoglycemic effect caused by insulin, which can cause severe and persistent hypoglycemia, which is more likely to occur when fasting or when there is less glycogen in the liver. Chloroquine, quinidine, quinine, etc. can delay the degradation of insulin, increase the insulin concentration in the blood, and thus enhance its hypoglycemic effect. Hyperglycemic drugs such as certain calcium channel blockers, clonidine, danazol, diazoxide, growth hormone, heparin, H2 receptor antagonists, marijuana, morphine, nicotine, sulfinpyrazone, etc. can change sugar metabolism and increase blood sugar. Therefore, the amount of insulin should be appropriately increased when used in combination with the above drugs. Angiotensin enzyme inhibitors, bromocriptine, clofibrate, ketoconazole, lithium, mebendazole, pyridoxine, theophylline, etc. can directly or indirectly reduce blood sugar in different ways. When insulin is used in combination with the above drugs, the amount should be appropriately reduced. Octreotide can inhibit the secretion of growth hormone, glucagon and insulin, and delay gastric emptying and slow gastrointestinal motility, causing delayed food absorption, thereby reducing postprandial hyperglycemia. When starting to use octreotide, the amount of insulin should be appropriately reduced, and then adjusted according to blood sugar. Smoking: Smoking can antagonize the blood sugar-lowering effect of insulin by releasing catecholamines. Smoking can also reduce the skin's absorption of insulin. Therefore, when smoking patients who are currently taking insulin suddenly quit smoking, they should observe changes in blood sugar and consider whether they need to reduce the amount of insulin appropriately.

Seal tightly and store in a cool place, avoid freezing.

10 ml: 400 units

24 months

Fosun Wanbang (Jiangsu) Pharmaceutical Group Co., Ltd.

• Founded in:

  1998-12-30

• Address:

  South side of Dongshan, Jinshanqiao Development Zone, Xuzhou City, Jiangsu Province

• Tax NO.:

  91320300714139872F

• Registered Funds:

  480.4554 million yuan

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