On ECHEMI
Home > Drugs > Compound Toin Ephedrine and Theophylline Tablets

Compound Toin Ephedrine and Theophylline Tablets

Function and Efficacy

This product is a compound preparation mainly based on phenytoin sodium and contains a variety of drugs with different mechanisms of action. Its main mechanism of action is: inhibiting the influx of Na+ and Ca2+ ions across the cell membrane, stabilizing the cell membrane of excitable cells such as bronchial smooth muscle and inflammatory cells; ephedrine hydrochloride stimulates beta;2 receptors, promotes the release of norepinephrine from nerve endings, enhances the contraction of the diaphragm, and is beneficial to improving respiratory function. Belladonna fluid extract and chlorpheniramine maleate can block the choline M receptors and histamine H1 receptors of bronchial smooth muscle, respectively, and relax bronchial smooth muscle. In addition, this product also has the effects of stimulating alpha; receptors on airway vascular smooth muscle, contracting airway blood vessels, inhibiting congestion and edema; inhibiting the release of allergic mediators, reducing capillary permeability; reducing viscosity by changing mucin synthesis; promoting airway ciliary movement, and enhancing diaphragmatic contraction. There is a good synergistic effect between the components of this product. Experiments have shown that this product has a good effect on histamine and acetylcholine. It has a significant antiasthmatic effect on asthma caused by antigens, and has a significant antitussive effect on various experimental coughs. This product also has a certain expectorant effect.

Ingredients

This product is a compound preparation, and its components are as follows: each tablet contains: phenytoin sodium 50 mg, chlorpheniramine maleate 1 mg, ephedrine hydrochloride 5 mg, caffeine 7.5 mg, theobromine 12.5 mg, theophylline 12.5 mg, and belladonna fluid extract 0.009 ml.

Name Description Content CAS NO. Manufacturer
Phenytoin sodiumIngredients

Inhibits the influx of Na+ and Ca2+ ions across cell membranes, and stabilizes the cell membranes of excitable cells such as bronchial smooth muscle and inflammatory cells

More
630-93-3 15
Chlorphenamine maleateIngredients

Blocks bronchial smooth muscle choline M receptors and histamine H1 receptors, relaxes bronchial smooth muscle, inhibits the release of allergic mediators, and reduces capillary permeability

More
113-92-8 28
TheobromineIngredients

Reduce viscosity by changing mucin synthesis; promote airway ciliary movement and enhance diaphragmatic contractility

More
83-67-0 9
TheophyllineIngredients

Reduce viscosity by changing mucin synthesis; promote airway ciliary movement and enhance diaphragmatic contractility

More
58-55-9 26

Appearance

This product is a sugar-coated tablet, which is white or off-white after removing the coating.

Indication

Used to relieve bronchospasm caused by bronchial asthma and chronic asthmatic bronchitis.

Usage and Dosage

Oral. Adults: 2 tablets at a time, 2 to 3 times a day, after meals. After taking it for one week or after the symptoms are controlled, the dosage can be reduced to 1 to 2 tablets each time, 1 to 2 times a day for maintenance. Maximum dosage: The maximum dosage at a time should not exceed 6 tablets, and the maximum dosage per day should not exceed 10 tablets. Children: 1/10 tablet per kilogram of body weight can be taken daily, and the maximum dosage per day should not exceed 5 tablets.

Adverse Reactions

Mild gastric discomfort, nausea and other gastrointestinal irritation symptoms. Long-term use may cause drowsiness, dizziness, etc. Gingival hyperplasia and hirsutism may also occur. Occasionally, allergic reactions such as rashes and liver damage may occur.

Precautions

1. Pregnant women are prohibited from using this product. 2. Patients with severe coronary heart disease or acute myocardial infarction are prohibited from using this product. 3. Patients who are allergic to this product are prohibited from using this product.

Special Population Medication

Precautions for children: This product can accelerate the metabolism of vitamin D. Long-term use by children may cause osteomalacia. Precautions for pregnancy and lactation: Pregnant women are prohibited from using this product. Precautions for the elderly: The elderly are more prone to drowsiness, so it is best to take it before going to bed. When using this product for a long time, the dosage should be slightly lower than that for adults.

Drug Interactions

1. This product can induce liver enzymes to accelerate the metabolism of a variety of drugs (such as adrenocortical hormone drugs, estrogen-containing contraceptives, etc.); 2. When used in combination with dicoumarol and liver enzyme inhibitors such as chloramphenicol, isoniazid, and para-aminosalicylic acid, the effect and toxicity of this product are enhanced.

Storage

Store in a moisture-proof, airtight, dry place.

Packaging Specification

Compound

Validity Period

Tentative 24 months

Manufacturer

Jilin Boda Pharmaceutical Co., Ltd.

  • Founded in:

    1995-06-26
  • Address:

    No. 58, Fortune Road, Liaoyuan Economic Development Zone, Jilin Province
  • Tax NO.:

    91220400125165140B
  • Registered Funds:

    62,724,684 yuan
  • Website:

  • Email:

Feedback & Suggestions
Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.