Metronidazole suppositories
Function and Efficacy
This product is a nitroimidazole derivative that can inhibit the redox reaction of amoeba and break the nitrogen chain of the protozoa. In vitro tests have shown that when the drug concentration is 1~2mg/L, the histolytica amoeba can undergo morphological changes in 6~20 hours and all are killed within 24 hours. When the concentration is 0.2mg/L, the histolytica amoeba can be killed within 72 hours. This product has a strong effect of killing trichomonas, and its mechanism is unknown. Metronidazole has a killing effect on cells and anaerobic microorganisms growing under hypoxic conditions. The metabolites generated when it is reduced in the human body also have anti-anaerobic effects, inhibiting the synthesis of bacterial deoxyribonucleic acid, thereby interfering with the growth and reproduction of bacteria, and ultimately causing bacterial death.
Ingredients
Metronidazole.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| MetronidazoleIngredients |
This product is a nitroimidazole derivative that can inhibit the redox reaction of amoeba and break the nitrogen chain of the protozoa. In vitro tests have shown that when the drug concentration is 1~2mg/L, the histolytica amoeba can undergo morphological changes in 6~20 hours and all are killed within 24 hours. When the concentration is 0.2mg/L, the histolytica amoeba can be killed within 72 hours. This product has a strong effect of killing trichomonas, and its mechanism is unknown. Metronidazole has a killing effect on cells and anaerobic microorganisms growing under hypoxic conditions. The metabolites generated when it is reduced in the human body also have anti-anaerobic effects, inhibiting the synthesis of bacterial deoxyribonucleic acid, thereby interfering with the growth and reproduction of bacteria, and ultimately causing bacterial death. More |
443-48-1 | 39 |
Appearance
This product is a milky white to light yellow fat-soluble suppository.
Indication
It is used to treat Trichomonas vaginitis. It can also be used to prevent and treat anaerobic infection after minor gynecological surgery.
Usage and Dosage
Vaginal administration: 0.5g at a time, 0.5g once every night, for 7 to 10 days. Metronidazole tablets should be taken at the same time, 0.2g each time, four times a day, for seven consecutive days.
Adverse Reactions
Same as tablets.
Precautions
It is forbidden to use in pregnant and lactating women.
Special Population Medication
Precautions for children: This experiment has not been conducted and there is no reliable reference. Precautions for pregnancy and lactation: Pregnant and lactating women are prohibited. Precautions for the elderly: This experiment has not been conducted and there is no reference.
Drug Interactions
Not yet clear.
Storage
Keep in a dark place, sealed and stored in a cool place below 30℃
Packaging Specification
0.5g
Validity Period
36 months.
Manufacturer
Zhejiang Shapuaisi Pharmaceutical Co., Ltd.
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Founded in:
2000-07-17 -
Address:
No. 1588, Xinming Road, Economic Development Zone, Pinghu City, Zhejiang Province -
Tax NO.:
91330000146644116H -
Registered Funds:
375.925005 yuan -
Website:
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Email: