Trifluoperazine Hydrochloride Tablets

This product is a phenothiazine antipsychotic. Its antipsychotic effect is related to its blocking of dopamine receptors in the brain, inhibiting dopamine receptors in the emetic chemoreceptor area of the medulla oblongata and directly inhibiting the vomiting center, producing a strong antiemetic effect, but weak sedative and anticholinergic effects.

The main ingredient of this product is trifluoperazine hydrochloride, and its chemical name is: 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-phenothiazine dihydrochloride.

This product is a sugar-coated tablet, which appears white after removing the sugar coating

It is used for various types of schizophrenia, has an invigorating and activating effect, and is suitable for the catatonic stupor symptoms and the emotional indifference and behavioral withdrawal symptoms of simple and chronic schizophrenia.

Oral administration starts with a low dose, 5 mg once, 2 to 3 times a day. Gradually increase to 5 to 10 mg once every 3 to 4 days, 2 to 3 times a day. The daily dose is 15 to 30 mg, and the highest dose is 45 mg a day.

Extrapyramidal reactions are common, such as akathisia, acute dystonia and Parkinson's disease. Long-term and excessive use may cause tardive dyskinesia. Palpitations, insomnia, fatigue, dry mouth, blurred vision, dysuria, constipation, galactorrhea, gynecomastia, menstrual disorders, amenorrhea, etc. may occur. Rarely, drowsiness, restlessness, dizziness, and urinary retention are seen. Allergic rash, leukopenia and malignant syndrome are occasionally seen. Occasionally, it may cause postural hypotension, palpitations or electrocardiogram changes, elevated liver enzyme levels or obstructive jaundice, and epilepsy.

Patients with basal ganglia lesions, Parkinson's disease, Parkinson's syndrome, bone marrow suppression, glaucoma, coma and allergy to phenothiazines.

Precautions for children: Children under 6 years old are prohibited from using this product. Children over 6 years old are prone to extrapyramidal symptoms, so the dosage should be reduced as appropriate. Precautions for pregnancy and lactation: Pregnant women should use this product with caution. Lactating women should stop breastfeeding while using this product. Precautions for the elderly: Elderly patients should start with a small dose and reduce the dosage as appropriate depending on the condition to reduce the occurrence of extrapyramidal reactions and tardive dyskinesia.

1. When used in combination with ethanol or other central nervous system depressants, it can enhance the central inhibitory effect. 2. When used in combination with antihypertensive drugs, it can easily cause postural hypotension. 3. When used in combination with sultopride, this product increases the risk of ventricular arrhythmia, and in severe cases, it can cause torsades de pointes arrhythmia. 4. When used in combination with other atropine drugs, adverse reactions are additive.

Keep in a sealed container

5mg

24 months

Guangzhou Baiyunshan Guanghua Pharmaceutical Co., Ltd.

• Founded in:

  1993-01-30

• Address:

  No.1 Nanshi Road, Haizhu District, Guangzhou

• Tax NO.:

  914401011904851166

• Registered Funds:

  55.285 million yuan

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