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Cyclic Adenosine Monophosphate Injection

Function and Efficacy

Cyclic adenosine monophosphate is a protein kinase activator and a derivative of nucleotides. It is an important substance with physiological activity that is widely present in the human body. It is generated by adenosine triphosphate under the catalysis of adenylate cyclase and can regulate various functional activities of cells. As the second messenger of hormones, it plays a role in regulating physiological functions and material metabolism in cells, can change the function of cell membranes, promote calcium ions in reticulum to enter muscle fibers, thereby enhancing myocardial contraction, and can promote the activity of respiratory chain oxidases, improve myocardial hypoxia, relieve symptoms of coronary heart disease and improve electrocardiograms. In addition, it plays an important role in regulating sugar, fat metabolism, nucleic acid, and protein synthesis.

Ingredients

The main ingredient of this product is: cyclic adenosine monophosphate. Its structural formula is: Molecular formula: C10H12N5O6P·H2O Molecular weight: 347.22

Name Description Content CAS NO. Manufacturer
Cyclic AMPIngredients

Cyclic adenosine monophosphate is a protein kinase activator and a derivative of nucleotides. It is an important substance with physiological activity that is widely present in the human body. It is generated by adenosine triphosphate under the catalysis of adenylate cyclase and can regulate various functional activities of cells. As the second messenger of hormones, it plays a role in regulating physiological functions and material metabolism in cells, can change the function of cell membranes, promote calcium ions in reticulum to enter muscle fibers, thereby enhancing myocardial contraction, and can promote the activity of respiratory chain oxidases, improve myocardial hypoxia, relieve symptoms of coronary heart disease and improve electrocardiograms. In addition, it plays an important role in regulating sugar, fat metabolism, nucleic acid, and protein synthesis.

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60-92-4 12

Appearance

This product is a colorless clear liquid.

Indication

1. Used for angina pectoris, myocardial infarction, myocarditis and cardiogenic shock; 2. It has a certain effect on improving symptoms such as palpitations, shortness of breath and chest tightness in rheumatic heart disease; 3. It can improve the efficacy of acute leukemia combined with chemotherapy, and can also be used to induce remission of acute leukemia; 4. In addition, it also has a certain effect on chronic bronchitis in the elderly, various hepatitis and psoriasis.

Usage and Dosage

For intravenous injection, 20 mg at a time, dissolved in 20 ml of 0.9% sodium chloride injection, bolus injection, twice a day. For intravenous drip, 40 mg of this product is dissolved in 250-500 ml of 5% glucose injection, once a day. Coronary heart disease is treated for 15 days, and can be used continuously for 2-3 courses; leukemia is treated for one month; psoriasis is treated for 2-3 weeks, which can be extended to 4-7 weeks, and the daily dosage can be increased to 60-80 mg.

Adverse Reactions

Fever and rash are occasionally seen. Large doses of intravenous injection (up to 0.5 mg/kg per minute) may cause abdominal pain, headache, myalgia, testicular pain, back pain, limb weakness, nausea, numbness of hands and feet, and high fever.

Precautions

People who are allergic to this product are prohibited from using it, and those with allergic constitutions should use it with caution.

Special Population Medication

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Not yet clear.

Drug Interactions

Not yet clear.

Storage

Keep away from light and store in a sealed container.

Packaging Specification

2ml:20mg

Validity Period

24 months

Manufacturer

Harbin Medisan Pharmaceutical Co., Ltd.

  • Founded in:

    1996-06-21
  • Address:

    Beijing Road, Limin Development Zone, Harbin
  • Tax NO.:

    91230100607168790X
  • Registered Funds:

    316.35755 million yuan
  • Website:

  • Email:

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