Valacyclovir Hydrochloride Tablets

This drug is a precursor of acyclovir. It is hydrolyzed into acyclovir in the body and inhibits viruses. It has a strong inhibitory effect on herpes simplex virus I (HSV-I) and herpes simplex virus II (HSV-II), but a weak inhibitory effect on varicella virus, Epstein-Barr virus and cytomegalovirus. Its mechanism of action is to limit the synthesis of viral DNA and inhibit its replication.

The content of valacyclovir hydrochloride (C13H20N6O4HCl) in this product should be 90.0-110.0% of the labeled amount.

This product is a film-coated tablet, which appears white or off-white after removing the film coating.

It is used to treat varicella zoster and herpes simplex virus infections of type I and type II, including primary and recurrent genital herpes virus infections. This product can be used for all indications of acyclovir.

Oral administration, 0.3g at a time, twice a day, before meals on an empty stomach. For herpes zoster, take the medicine for 10 consecutive days. For herpes simplex, take the medicine for 7 consecutive days.

Use with caution in patients with renal insufficiency, children and breastfeeding women. The safety and efficacy data of this drug for children under two years old have not yet been established. Drink plenty of water during medication. It is contraindicated for those who are allergic to acyclovir.

It is contraindicated for those who are allergic to this product and acyclovir.

Precautions for children: The safety and effectiveness of the drug for children have not yet been determined. Precautions for pregnancy and lactation: Acyclovir can pass through the placenta, and pregnant women need to weigh the pros and cons of using the drug. The concentration of acyclovir in breast milk is 0.6 to 4.1 times the blood concentration, so lactating women should use it with caution. Precautions for the elderly: Due to the decline of physiological renal function, the dosage and medication interval of this product need to be adjusted.

1. Combination with zidovudine can cause nephrotoxicity, manifested as deep lethargy and fatigue. 2. Competitive inhibition of organic acid secretion with probenecid. Combination with probenecid can slow down the excretion of acyclovir, prolong the half-life, and cause drug accumulation in the body.

Seal tightly and store in a cool, dry place.

0.3 g

36 months.

Sichuan MED-SHINE Pharmaceutical Co., Ltd.

• Founded in:

  1998-09-15

• Address:

  No. 1069, Tsingtao Beer Avenue, Chengdu Cross-Strait Science and Technology Industrial Development Park, Wenjiang District, Chengdu

• Tax NO.:

  9151011570915754XK

• Registered Funds:

  50 million yuan

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