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Metformin Hydrochloride Enteric-coated Capsules

Function and Efficacy

This product belongs to the biguanide hypoglycemic drug and does not promote the secretion of insulin. Its hypoglycemic effect is to promote tissue anaerobic glycolysis, enhance the use of glucose by muscle and other tissues, and at the same time inhibit the synthesis of liver glycogen, reduce the production of liver sugar, and lower blood sugar.

Ingredients

The main ingredient of this product is: metformin hydrochloride.

Name Description Content CAS NO. Manufacturer
1,1-DIMETHYLBIGUANIDE HYDROCHLORIDEIngredients

This product belongs to the biguanide hypoglycemic drug and does not promote the secretion of insulin. Its hypoglycemic effect is to promote tissue anaerobic glycolysis, enhance the use of glucose by muscle and other tissues, and at the same time inhibit the synthesis of liver glycogen, reduce the production of liver sugar, and lower blood sugar.

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15537-72-1 55

Appearance

This product is an enteric-coated capsule, and the contents are white crystalline powder.

Indication

It is used for patients with type 2 diabetes who are not satisfied with diet control alone, especially obese patients. It not only has the effect of lowering blood sugar, but also may have the effect of reducing weight. It is effective for some cases where sulfonylureas are ineffective. If used in combination with sulfonylurea hypoglycemic drugs, it has a synergistic effect, and the effect is better than that of each of them.

Usage and Dosage

Oral administration, half an hour before meals. Adults start with 0.25g at a time, 2 to 3 times a day. The dose can be adjusted based on blood sugar and urine sugar levels. The maximum daily dose should not exceed 2g, or follow the doctor's advice.

Adverse Reactions

1. Gastrointestinal reactions, manifested as loss of appetite, nausea, vomiting, diarrhea, stomach pain, and metallic taste in the mouth. 2. Sometimes there is weakness, tiredness, weight loss, dizziness, and rash.

Precautions

It is contraindicated for patients with type 12 diabetes accompanied by ketosis, acidosis, liver and kidney dysfunction, heart failure, respiratory failure, acute myocardial infarction, severe infection and trauma, major surgery, and clinical hypotension and hypoxia. 2. It is contraindicated for patients who drink excessively, are dehydrated, have dysentery, are malnourished, and are allergic to this product and biguanides.

Special Population Medication

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Contraindicated for pregnant and lactating women. Precautions for the elderly: Patients over 70 years old may develop lactic acidosis and should be used with caution.

Drug Interactions

1. This drug combined with insulin will enhance the hypoglycemic effect, and the insulin dose should be reduced. 2. It can enhance the anticoagulant effect of anticoagulants (such as warfarin), leading to bleeding tendency. 3. This product can cause abdominal pain, acidosis and hypothermia if taken with alcoholic beverages. 4. This product can cause hypoglycemia when used in combination with sulfonylureas.

Storage

Keep tightly closed.

Packaging Specification

0.25g

Validity Period

24 months

Manufacturer

Shenzhen Zhonglian Pharmaceutical Co., Ltd.

  • Founded in:

    1988-10-11
  • Address:

    Room 401, Building 1, Block B, No. 9 Danqing Road, Jinsha Community, Kengzi Street, Pingshan District, Shenzhen (One license, multiple locations enterprise)
  • Tax NO.:

    91440300192188676Y
  • Registered Funds:

    120 million yuan
  • Website:

  • Email:

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