Cefotezol Sodium for Injection

β-lactam antibiotics, cephalosporins

This product is a sterile powder of ceftezole sodium. Its chemical name is: sodium (6R, 7R)-3-[(1,3,4-thiadiazol-2-yl)thiomethyl]-8-oxo-7-[2-(1H-tetrazol-1-yl)acetylamino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate.

Sepsis, pneumonia, bronchitis, bronchiectasis (in case of infection), secondary infection of chronic respiratory diseases, lung abscess, peritonitis, pyelonephritis, cystitis, urethritis.

1. Adults: daily dose is 0.5-4g, divided into 1-2 times for intravenous administration or intramuscular injection. 2. Children: daily dose is 20-80mg/kg body weight, divided into 1-2 times for intravenous administration or intramuscular injection. #Preparation of injection 1. Intravenous injection: dissolve in sterile water for injection, 0.9% sodium chloride injection or 5% glucose injection, and inject slowly. 2. Intravenous drip: dissolve in normal saline or 5% glucose injection. 3. Intramuscular injection: dissolve in 0.5% lidocaine hydrochloride injection. #If the injection becomes turbid due to temperature reasons when it is dissolved, it can be heated to clarify it before use. It is best to use it immediately after dissolution.

1. Shock: Shock rarely occurs, and close observation is required. If any symptoms related to the use of this product occur, such as discomfort, abnormal sensation in the mouth, asthma, dizziness, sudden abnormal bowel movements, tinnitus, sweating, etc., the drug should be stopped immediately and necessary treatment should be given. 2. A few have allergic reactions, such as rash, urticaria, skin redness, itching, fever, etc., which disappear when the drug is stopped. 3. Severe renal function abnormalities are rare, and blood creatinine is occasionally increased. If abnormalities are found, the drug should be stopped immediately and necessary treatment should be given. 4. Granulocytopenia, leukopenia, eosinophilia, thrombocytopenia, etc. are rare. When the above abnormalities are found, the drug should be stopped. 5. GOT, GPT, and alkaline phosphatase increase are rare. When the above abnormalities occur, the drug should be stopped immediately. 6. Gastrointestinal reactions, such as nausea, vomiting, diarrhea, etc. are rare, and pseudomembranous colitis is rare. When abdominal pain and diarrhea occur, the drug should be stopped immediately. 7. Dysbacteriosis: Candida infection rarely occurs. 8. Vitamin deficiency: Vitamin K deficiency and B vitamin deficiency are rare. 9. Interstitial pneumonia, toxic fever, cough, dyspnea, abnormal chest X-ray, eosinophilia are rare. When the above symptoms occur, the drug should be discontinued and appropriate treatment should be given. 10. Others: Headache, general malaise, fever, superficial glossitis are rare.

1. Patients with a history of allergy to this product or cephalosporin antibiotics are contraindicated. 2. Patients with a history of allergy to lidocaine or acylanilide local anesthetics (this contraindication is limited to patients receiving intramuscular injections) are contraindicated.

Not yet clear.

Place in a cool place

0.5g (calculated based on 3 pieces of C13H12N8O4)