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Roxithromycin Capsules

Function and Efficacy

This product is a semi-synthetic 14-membered macrolide antibiotic. Its antibacterial spectrum and antibacterial effect are basically similar to those of erythromycin. Its effect on Gram-positive bacteria is slightly worse than that of erythromycin, but its effect on Legionella pneumophila is stronger than that of erythromycin. Its antimicrobial effect on Chlamydia pneumoniae, Mycoplasma pneumoniae, and Ureaplasma urealyticum is similar to or slightly stronger than that of erythromycin.

Ingredients

The main ingredient of this product is roxithromycin, and its chemical name is 9-[O-[(2-methoxyethoxy)-methyl]oxime]erythromycin.

Name Description Content CAS NO. Manufacturer
RoxithromycinIngredients

This product is a semi-synthetic 14-membered macrolide antibiotic. Its antibacterial spectrum and antibacterial effect are basically similar to those of erythromycin. Its effect on Gram-positive bacteria is slightly worse than that of erythromycin, but its effect on Legionella pneumophila is stronger than that of erythromycin. Its antimicrobial effect on Chlamydia pneumoniae, Mycoplasma pneumoniae, and Ureaplasma urealyticum is similar to or slightly stronger than that of erythromycin.

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80214-83-1 28

Appearance

This product is a hard capsule, and the contents are white or off-white powder and granules.

Indication

This product is suitable for pharyngitis and tonsillitis caused by Streptococcus pyogenes, sinusitis, otitis media, acute bronchitis, acute exacerbation of chronic bronchitis caused by sensitive bacteria, pneumonia caused by Mycoplasma pneumoniae or Chlamydia pneumoniae; urethritis and cervicitis caused by Chlamydia trachomatis; skin and soft tissue infections caused by sensitive bacteria.

Usage and Dosage

Oral administration on an empty stomach, generally for 5 to 12 days. Adults: 150 mg once, twice a day; 300 mg once a day is also acceptable. Children: 2.5 to 5 mg/kg per body weight, twice a day.

Adverse Reactions

The main adverse reactions are gastrointestinal reactions such as abdominal pain, diarrhea, nausea, and vomiting, but the incidence is significantly lower than that of erythromycin. Occasionally, there are rash, itchy skin, dizziness, headache, abnormal liver function (increased ALT and AST), and decreased peripheral blood cells.

Precautions

Patients who are allergic to this product, erythromycin or other macrolide drugs are contraindicated.

Special Population Medication

Precautions for children: Not clear. Precautions for pregnancy and lactation: Use with caution in pregnant and lactating women. A dosage of less than 0.05% is excreted into breast milk. Although there are reports that it has little effect on infants, it is still necessary to consider whether to stop breastfeeding. Precautions for the elderly: If there is no significant change in pharmacokinetics in the elderly, there is no need to adjust the dose.

Drug Interactions

1. It is not compatible with ergotamine, dihydroergotamine, bromocriptine, terfenadine, ketoconazole and cisapride. 2. It has little effect on the metabolism of aminophylline and has little effect on carbamazepine, warfarin, ranitidine and other antacids.

Storage

Sealed, store in a dry place.

Packaging Specification

75mg

Validity Period

24 months.

Manufacturer

Hainan Sanye Pharmaceutical Factory Co., Ltd.

  • Founded in:

    1989-01-19
  • Address:

    No. 6, Sanye East Road, Longhua District, Haikou City, Hainan Province
  • Tax NO.:

    914600002012496387
  • Registered Funds:

    10 million yuan
  • Email:

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