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Levofloxacin Lactate Sodium Chloride Injection

Function and Efficacy

It is the levorotatory form of ofloxacin, and its antibacterial activity is about twice that of ofloxacin. Its main mechanism of action is to inhibit bacterial DNA gyrase activity and inhibit bacterial DNA replication. It has the characteristics of broad antibacterial spectrum and strong antibacterial effect. It has strong antibacterial activity against most Enterobacteriaceae, such as Klebsiella pneumoniae, Proteus, Salmonella typhi, Shigella, influenza bacillus, some Escherichia coli, Pseudomonas aeruginosa, and gonococci; it also has good antibacterial effect against some Staphylococci, Streptococcus pneumoniae, Chlamydia, etc.

Ingredients

The main ingredient of this product is levofloxacin lactate.

Name Description Content CAS NO. Manufacturer
LEVOFLOXACIN LACTATEIngredients

It is the levorotatory form of ofloxacin, and its antibacterial activity is about 2 times that of ofloxacin. Its main mechanism of action is to inhibit bacterial DNA gyrase activity and inhibit bacterial DNA replication. It has the characteristics of broad antibacterial spectrum and strong antibacterial effect. It has strong antibacterial activity against most Enterobacteriaceae (such as Klebsiella pneumoniae, Proteus, Salmonella typhi, Shigella, influenza bacillus, some Escherichia coli, Pseudomonas aeruginosa, gonococci, etc.); it also has good antibacterial effect against some Staphylococci, Streptococcus pneumoniae, Chlamydia, etc.

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294662-18-3 11

Appearance

This product is a yellowish green clear liquid.

Indication

This product is suitable for the following moderate and severe infections caused by sensitive bacteria: respiratory system infections: acute bronchitis, acute exacerbation of chronic bronchitis, diffuse bronchiolitis, bronchiectasis and infection, pneumonia, tonsillitis (peritonsillar abscess); urinary system infections: pyelonephritis, complicated urinary tract infection, etc.; reproductive system infections: acute prostatitis, acute epididymitis, uterine cavity infection, uterine adnexitis, pelvic inflammatory disease (metronidazole can be used in combination when anaerobic infection is suspected); skin and soft tissue infections: infectious impetigo, cellulitis, lymphangiitis (adenitis), subcutaneous abscess, perianal abscess, etc.; intestinal infections: bacillary dysentery, infectious enteritis, salmonella enteritis, typhoid and paratyphoid; various infections in patients with sepsis, neutropenia and immunodeficiency; other infections: mastitis, trauma, burns and postoperative wound infection, abdominal infection (metronidazole can be used in combination when necessary), cholecystitis, cholangitis, bone and joint infection and ENT infection, etc.

Usage and Dosage

Intravenous drip: Adults: 0.1-0.2g at a time, twice a day, or as directed by a doctor; for patients with severe infection and pathogens with poor sensitivity to this product (such as Pseudomonas aeruginosa), the maximum daily dose can be increased to 600mg, divided into 2 intravenous drips.

Adverse Reactions

During medication, you may experience symptoms such as nausea, vomiting, abdominal discomfort, diarrhea, loss of appetite, abdominal pain, and bloating; neurological symptoms such as insomnia, dizziness, and headache; rash, itching, erythema, and redness, itching, or phlebitis at the injection site. Transient liver function abnormalities may also occur, such as increased blood transaminase and increased serum total bilirubin. Occasionally, blood urea nitrogen rises, fatigue, fever, palpitations, abnormal taste, and vascular irritation symptoms after injection, which are generally tolerated and disappear after the end of the course of treatment.

Precautions

It is contraindicated for patients who are allergic to quinolones, epileptic patients, pregnant and lactating women, and patients under 18 years of age.

Drug Interactions

1. This product cannot be used in the same infusion tube with solutions of polyvalent metal ions such as magnesium and calcium. 2. This product may cause convulsions when used in combination with phenylpropionic acid, fentanyl, and non-steroidal anti-inflammatory analgesics, so its combination should be avoided. 3. Avoid using it simultaneously with theophylline. If it is necessary to use it simultaneously, the blood concentration of theophylline should be monitored to adjust its dosage. 4. When used simultaneously with warfarin or its derivatives, the prothrombin time or other coagulation tests should be monitored. 5. When used simultaneously with oral hypoglycemic drugs, it may cause hypoglycemia. Therefore, attention should be paid to monitoring blood sugar concentration during medication. Once hypoglycemia occurs, this product should be discontinued immediately and appropriate treatment should be given.

Storage

Keep in a dark, airtight, cool place.

Packaging Specification

100 ml: 0.2 g of levofloxacin lactate (calculated as levofloxacin) and 0.9 g of sodium chloride

Manufacturer

Liaoning Hishen Liansheng Pharmaceutical Co., Ltd.

  • Founded in:

    2001-02-27
  • Address:

    No. 3, Jinquan Road, Langtou Town, Dandong City
  • Tax NO.:

    912106007268406746
  • Registered Funds:

    30 million yuan
  • Website:

  • Email:

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