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Amoxicillin dry suspension

Function and Efficacy

Broad-spectrum semi-synthetic penicillin has antibacterial effects on hemolytic streptococci, viridans streptococci, pneumococci, penicillin G-sensitive Staphylococcus aureus, gonococci, Haemophilus influenzae, enterococci, Salmonella, Salmonella typhi and Proteus. It has no effect on Staphylococcus aureus that produces penicillinase. Bacteria have complete cross-resistance to this product and ampicillin.

Ingredients

Chemical name: (2S,5R,6R)-3,3-dimethyl-6-[(R)-(-)-2-amino-2-(4-hydroxyphenyl)acetylamino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid trihydrate

Appearance

This product is a dry suspension.

Indication

Amoxicillin is suitable for the following infections caused by sensitive bacteria (non-β-lactamase-producing strains): 1. Upper respiratory tract infections such as otitis media, sinusitis, pharyngitis, tonsillitis, etc. caused by hemolytic streptococci, streptococci pneumoniae, staphylococci or Haemophilus influenzae. 2. Urogenital tract infections caused by Escherichia coli, Proteus mirabilis or Enterococcus faecalis. 3. Skin and soft tissue infections caused by hemolytic streptococci, staphylococci or Escherichia coli. 4. Lower respiratory tract infections such as acute bronchitis and pneumonia caused by hemolytic streptococci, streptococci pneumoniae, staphylococci or Haemophilus influenzae. 5. Acute simple gonorrhea. 6. This product can also be used to treat typhoid fever, typhoid carriers and leptospirosis; amoxicillin can also be used in combination with clarithromycin and lansoprazole to eradicate gastric, ten-dose

Usage and Dosage

Oral administration. The absorption of this product in the gastrointestinal tract is not affected by food, so it can be taken on an empty stomach or after meals, and can be taken with food such as milk. Tear open the small bag, pour the powder into an appropriate amount of boiled water, shake well and take it; add 42ml of boiled water to the bottled 1250mg/bottle, shake well to get 50ml suspension, (each 5ml contains 125mg of amoxicillin); add 84ml of boiled water to the bottled 2500mg/bottle, shake well to get 100ml suspension, (each 5ml contains 125mg of amoxicillin). Children take 6.7-13.3mg/kg according to body weight, once every 8 hours or as directed by a doctor. Adults with general infection take 500mg once, once every 6-8 hours; patients with severe symptoms can increase to 1000mg once, once every 6-8 hours or as directed by a doctor. Amoxicillin dry suspension reference dosage for children: age 125mg/bag/time 250mg/bag/time bottle/time daily dosage: under one year old 0.5 bag 2.5ml once every 8 hours 1-3 years old 1 bag 1/2 bag 5ml 3-5 years old 1.5 bags 3/4 bag 7.5ml 5-10 years old 2 bags 1 bag 10ml 10 years old and above 2-3 bags 1-11/2 bags 10-15ml

Adverse Reactions

1. Gastrointestinal reactions such as nausea, vomiting, diarrhea and pseudomembranous colitis. 2. Allergic reactions such as rash, drug fever and asthma. 3. Anemia, thrombocytopenia, eosinophilia, etc. 4. Serum aminotransferase may be slightly elevated. 5. Superinfection caused by Candida or drug-resistant bacteria. 6. Occasionally, central nervous system symptoms such as excitement, anxiety, insomnia, dizziness and abnormal behavior may occur.

Precautions

It is contraindicated in patients with penicillin allergy or penicillin skin test positive.

Special Population Medication

Precautions during pregnancy and lactation: Animal reproduction studies have shown that amoxicillin at 10 times the human dose did not damage the fertility and fetus of rats and mice. However, there is still a lack of adequate control studies in humans. Given that animal reproduction studies cannot fully predict human reactions, pregnant women should only use this product when it is necessary. Since a small amount of amoxicillin can be secreted in breast milk, breastfeeding mothers may cause allergies in their babies.

Drug Interactions

1. Probenecid competitively reduces the renal tubular secretion of this product. The simultaneous use of the two can cause an increase in the blood concentration of amoxicillin and a prolonged half-life. 2. Chloramphenicol, macrolides, sulfonamides and tetracyclines interfere with the antibacterial effect of amoxicillin in vitro, but the clinical significance is unclear.

Storage

Keep away from light and store in sealed container.

Packaging Specification

0.25g (based on C16H19N3O5 tablets)

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