Cefuroxime dry suspension

This product is a first-generation cephalosporin, which has good antibacterial effect on some strains of Gram-positive cocci such as non-penicillinase-producing and penicillinase-producing Staphylococcus aureus, coagulase-negative Staphylococci, group A hemolytic streptococci, Streptococcus pneumoniae and viridans streptococci. Anaerobic Gram-positive bacteria are mostly sensitive to this product, and Bacteroides fragilis is resistant to this product. Methicillin-resistant Staphylococci and Enterococci are resistant to this product. The effect of this product on Gram-positive and Gram-negative bacteria is similar to that of cephalexin. This product has a certain effect on gonococci and is also active against enzyme-producing gonococci; its activity against Haemophilus influenzae is poor.

The main ingredient of this product is cefradine, and its chemical name is: (6R,7R)-7[(R)-2-amino-2-(1,4-cyclohexenyl)acetylamino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4,2,0]oct-2-ene-2-carboxylic acid.

This product is a powder with flavoring agent; it has a fragrant smell and sweet taste.

It is suitable for acute pharyngitis, tonsillitis, otitis media, bronchitis, pneumonia and other respiratory tract infections, urogenital tract infections and skin and soft tissue infections caused by sensitive bacteria. This product is an oral preparation and should not be used for severe infections.

Oral administration: 0.25-0.5g for adults, 4 times a day, with a maximum daily dose of 4g. For children, 6.25-12.5ml/kg for children, 4 times a day, based on body weight. Add drinking water to the mark on the bottle and shake well to form a suspension. Store the suspension at room temperature and consume it within 7 days; store it in a refrigerator and consume it within 14 days.

The adverse reactions of this product are mild and the incidence is low, about 6%. Gastrointestinal reactions such as nausea, vomiting, diarrhea, and upper abdominal discomfort are more common. The incidence of drug rash is about 1% to 3%. Pseudomembranous colitis, eosinophilia, positive reaction to direct Coombs test, peripheral blood leukocytopenia and neutrophil granulocyte reduction are seen in individual patients. A small number of patients may experience temporary increase in blood urea nitrogen, serum aminotransferase, and serum alkaline phosphatase.

This product is contraindicated in patients who are allergic to cephalosporins or have a history of anaphylactic shock or immediate reaction to penicillin.

Precautions for children: Adverse reactions reported after domestic marketing may cause hematuria when using this product. Children are susceptible to the disease. Children should be cautious when using this product and use it under monitoring. Precautions during pregnancy and lactation: Because this product can enter the fetal blood circulation through the blood-placental barrier, pregnant women need to have specific indications for medication. This product can also enter breast milk in small amounts. Although there have been no reports of problems with the use of cephalosporins in lactating women, it still needs to be used after weighing the pros and cons. Precautions for the elderly: Elderly patients with impaired renal function should appropriately reduce the dose or extend the dosing interval.

1. Cephalosporins can delay the excretion of phenytoin sodium in the renal tubules. 2. Phenylbutazone combined with cephalosporin antibiotics can increase renal toxicity. 3. Combined with strong diuretics, it can increase renal toxicity. 4. Combined with mecillinam, it has a synergistic effect on gram-negative bacteria such as Escherichia coli and Salmonella. 5. Probenecid can delay the renal excretion of this product.

Seal and store in a cool and dark place (no higher than 20℃). Validity period: 24 months

Calculated as C16H19N3O4S 0.125g

24 months

Guangdong Xinfeng Pharmaceutical Co., Ltd.

• Founded in:

  1995-09-28

• Address:

  Hongbo Industrial Zone, Boluo County

• Tax NO.:

  914413001961374115

• Registered Funds:

  102 million yuan

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