Pefloxacin Mesylate Injection
Function and Efficacy
Pefloxacin mesylate is a quinolone antibacterial drug, and its mechanism of action is to inhibit bacterial DNA helicase. It has a broad-spectrum antibacterial effect, and has strong antibacterial activity against Enterobacter bacteria such as Escherichia coli, Klebsiella, Proteus, Shigella, Salmonella typhi, etc., as well as influenza bacillus, Neisseria, etc. It also has a certain antibacterial effect on Staphylococcus aureus and Pseudomonas aeruginosa. It has only a mild effect on pneumococci, various groups of streptococci and enterococci.
Ingredients
The main ingredient of this product is pefloxacin mesylate.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Pefloxacin mesylateIngredients |
Quinolone antibacterial drugs inhibit bacterial DNA helicase and have a broad-spectrum antibacterial effect. They have strong antibacterial activity against Enterobacter bacteria such as Escherichia coli, Klebsiella, Proteus, Shigella, Salmonella typhi, etc., as well as influenza bacillus and Neisseria. They also have certain antibacterial effects on Staphylococcus aureus and Pseudomonas aeruginosa. They have only mild effects on pneumococci, various groups of streptococci and enterococci. More |
70458-95-6 | 4 |
Indication
Various infections caused by pefloxacin-sensitive bacteria: urinary tract infections; respiratory tract infections; ear, nose and throat infections; gynecological and reproductive system infections; abdominal and liver and gallbladder system infections; bone and joint infections; skin infections; sepsis and endocarditis; meningitis.
Usage and Dosage
Intravenous drip: Common adult dosage, 0.4g at a time, add to 250ml of 5% glucose solution and slowly drip intravenously, once every 12 hours. Patients with jaundice should take the medicine once a day; patients with ascites should take the medicine once every 36 hours; patients with jaundice and ascites should take the medicine once every 48 hours. Or follow the doctor's advice.
Adverse Reactions
A small number of patients may experience: 1. Gastrointestinal reactions, such as nausea, vomiting, loss of appetite, diarrhea, etc. 2. Photosensitivity reactions, nervous system reactions, such as dizziness, vertigo, headache, tremor, insomnia, etc. 3. Rash, increased serum aspartate aminotransferase and alanine aminotransferase, decreased white blood cells, etc. 4. Occasionally, local irritation symptoms after injection. The above reactions are all mild to moderate reactions and will disappear after stopping the drug.
Precautions
1. Use with caution in patients with central nervous system diseases; 2. Patients who are allergic to this product or other quinolones, or those with insufficient 6-phosphate glucose dehydrogenase are prohibited from using this product; 3. Pregnant and lactating women are prohibited from using this product; 4. Patients under 18 years old are prohibited from using this product.
Special Population Medication
Precautions for children: Not for use in patients under 18 years of age. Precautions for pregnancy and lactation: Not for use in pregnant or lactating women.
Drug Interactions
1 Avoid taking theophylline, magnesium or aluminum hydroxide antacids at the same time. 2 Do not use sodium chloride solution or other solutions containing chloride ions as diluent.
Storage
Keep away from light, tightly closed, in a cool place.
Packaging Specification
5ml:0.4g (calculated according to C17H20FN303)