Ethylamine, pyrazine, and rifampicin tablets

Not yet clear.

Each tablet contains 0.15g of rifampicin (C43H58N4O12), 0.075g of isoniazid (C6H7N3O), 0.4g of pyrazinamide (C5H5N3O), and 0.275g of ethambutol hydrochloride (C10H24N2O2·2HCl).

This product is a white tablet.

It is suitable for the initial 2 months of intensive treatment of short-term tuberculosis therapy and must be taken daily during this stage.

Oral administration. Patients weighing 30-37kg should take 2 tablets per day, patients weighing 38-54kg should take 3 tablets per day, patients weighing 55-70kg should take 4 tablets per day, and patients weighing more than 71kg should take 5 tablets per day, one hour before meals. This product is not suitable for patients weighing less than 30kg.

Not yet clear.

1. Patients who are allergic to rifampicin, pyrazinamide, isoniazid, ethambutol hydrochloride or any excipients are contraindicated; 2. Patients with abnormal liver function, biliary obstruction, pregnant women within 3 months, gout patients, mental illness, epilepsy patients, diabetic patients with fundus lesions, and porphyria are contraindicated. 3. Patients with severe renal insufficiency (creatinine clearance ﹤30ml/min) are contraindicated. 4. Contraindicated for combined use with voriconazole and protease inhibitors (see [Drug Interactions] for details).

Precautions for children: This product is not suitable for children. Precautions for pregnancy and lactation: It is contraindicated for pregnant women in the first 3 months of pregnancy. If the drug may benefit the patient, this treatment option should be considered. This product can only be used when the potential benefit to the mother outweighs the potential risk to the fetus. Precautions for the elderly: The elderly are often accompanied by physiological renal impairment, so the dosage should be adjusted according to renal function. Or follow the doctor's advice.

1. Effects of other drugs on this product: Antacids can reduce the bioavailability of rifampicin, isoniazid, and ethambutol. To avoid this, this product should be taken 1 hour after taking antacids. Corticosteroids can reduce the blood concentration of isoniazid by promoting its metabolism and/or increasing renal clearance. 2. Effects of this product on other drugs: Rifampicin has a strong induction effect on the cytochrome P450 system (CYP450). The cytochrome P450 system is mainly composed of two subfamilies, CYP3A and CYP2C, which account for 80% of the cytochrome P450 system isoenzymes.

seal.

Each tablet contains 120 mg of rifampicin, 120 mg of isoniazid, 400 mg of pyrazinamide, and 250 mg of ethambutol hydrochloride.

24 months

Shenyang Red Flag Pharmaceutical Co., Ltd.

• Founded in:

  1998-10-30

• Address:

  No. 6 Xinluo Street, Hunnan New District, Shenyang

• Tax NO.:

  912101121178724277

• Registered Funds:

  100 million yuan

• Website:

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• Email:

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