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Bromhexine Hydrochloride for Injection

Function and Efficacy

1 Pharmacology: This drug is a semi-synthetic product obtained from vasicine, which has the effect of reducing and breaking mucopolysaccharide fibers in sputum, reducing sputum viscosity, making sputum thinner and easier to cough up. Secondly, it can inhibit the synthesis of acidic glycoproteins in mucous glands and goblet cells, reduce the content of sialic acid (one of the components of acidic mucopolysaccharides) in sputum, reduce sputum viscosity, and facilitate sputum coughing up. The expectorant effect of this drug is also related to its promotion of ciliary movement of the respiratory mucosa and its malignant expectorant effect. As sputum is coughed up, the patient's ventilation can be improved. 2 Toxicology: Acute toxicity: Rabbit oral LD50 10g/kg, rat oral LD50 is 16.65g/kg. Animal reproduction

Ingredients

N-Methyl-N-cyclohexyl-2-amino-3,5-dibromobenzylamine hydrochloride

Appearance

This product is white loose mass or powder.

Indication

It is mainly used for patients with chronic bronchitis and other respiratory diseases such as asthma, bronchiectasis, silicosis, etc. who have sticky phlegm that is difficult to cough up.

Usage and Dosage

Intravenous drip: dilute with 0.9% sodium chloride injection or 5% glucose injection and then drip intravenously, 4 mg (1 vial) at a time, 8-12 mg (2-3 vials) per day.

Adverse Reactions

1. Minor adverse reactions: Occasionally headache, dizziness, nausea, vomiting, stomach discomfort, abdominal pain, diarrhea, which may disappear after reducing the dosage or stopping the drug. There may be a transient increase in serum transaminase. 2. Serious adverse reactions: rash, enuresis.

Precautions

It is contraindicated for those who are allergic to this product.

Drug Interactions

No relevant reports have been found.

Storage

Keep in a dark, airtight, cool place. Tentatively 12 months.

Packaging Specification

4mg

Manufacturer

Ma'anshan Fengyuan Pharmaceutical Co., Ltd.

  • Founded in:

    2008-06-26
  • Address:

    No. 1503, Meishan Road, Economic and Technological Development Zone, Ma'anshan City, Anhui Province
  • Tax NO.:

    913405006758985090
  • Registered Funds:

    145.5 million yuan
  • Email:

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