Amoxicillin and clavulanate potassium dispersible tablets (2:1)

This product is a compound preparation of amoxicillin and potassium clavulanate. Amoxicillin is a broad-spectrum penicillin antibiotic. Potassium clavulanate itself has only weak antibacterial activity, but has a strong broad-spectrum beta-lactamase inhibitory effect. The combination of the two can protect amoxicillin from beta-lactamase hydrolysis. The antibacterial spectrum of this product is the same as that of amoxicillin, and has been expanded. It has a good effect on enzyme-producing Staphylococcus aureus, Staphylococcus epidermidis, coagulase-negative Staphylococci and enterococci. It also has good antibacterial activity against some beta-lactamase-producing Enterobacteriaceae, Haemophilus influenzae, Moraxella catarrhalis, Bacteroides fragilis, etc. This product has no effect on methicillin-resistant Staphylococcus aureus and Enterobacter, which produce chromosome-mediated type I enzymes, and Pseudomonas.

This product is a compound preparation, its components are amoxicillin and clavulanate potassium.

This product is off-white or light yellow tablets.

This product is suitable for various infections caused by sensitive bacteria: respiratory tract infections, ear, nose and throat infections, skin and soft tissue infections, urinary and reproductive system infections, and other infections, etc.

This product can be swallowed directly, or placed in an appropriate amount of warm water, stirred until completely dissolved and then added. Adults and children over 12 years old, 2 tablets each time, three times a day; children aged 7 to 12 years old, 1.5 tablets each time, three times a day; children aged 1 to 7 years old, one tablet each time, three times a day; children aged 3 months to 1 year old, 0.5 tablets each time, three times a day; in case of severe infection, the dose can be doubled or followed the doctor's advice. Without reexamination, the continuous treatment period shall not exceed 14 days.

Not yet clear.

It is contraindicated in patients who are allergic to penicillins or have liver dysfunction.

Precautions for children: Children over 12 years old, 2 tablets each time, three times a day; children 7-12 years old, 1.5 tablets each time, three times a day; children 1-7 years old, 1 tablet each time, three times a day; children 3 months to 1 year old, 0.5 tablets each time, three times a day. Precautions for pregnancy and lactation: 1. This product can pass through the placenta, and the concentration in umbilical cord blood is 1/4 to 1/3 of the maternal blood concentration, so it is forbidden for pregnant women. 2. This product can be secreted into breast milk, which may sensitize infants and cause diarrhea, rash, Candida infection, etc., so lactating women should use it with caution or suspend breastfeeding during medication. Precautions for the elderly: Elderly patients should adjust the dosage or medication interval according to their renal function.

1. Aspirin, indomethacin, phenylbutazone, sulfonamides, and probenecid can reduce the excretion of this product in the renal tubules, thereby increasing the blood concentration of this product, prolonging the blood elimination half-life (t1/2β), and possibly increasing the toxicity. 2. When this product is used in combination with allopurinol, the incidence of rash increases significantly, so it should be avoided. 3. This product should not be used in combination with acetaldehyde dehydrogenase inhibitors such as disulfiram. 4. When this product is used in combination with chloramphenicol for bacterial meningitis, the incidence of long-term sequelae is higher than when either is used alone. 5. This product can stimulate estrogen metabolism or reduce its enterohepatic circulation, thus reducing the effectiveness of oral contraceptives. 6. Antibiotics such as chloramphenicol, erythromycin, tetracyclines, and antibacterial drugs such as sulfonamides can interfere with the bactericidal activity of this product, so it should not be used in combination with this product, especially in the treatment of meningitis or severe infections that urgently require bactericidal drugs. 7. This product can enhance the effect of warfarin. 8. Aminoglycoside antibiotics can generally enhance the in vitro bactericidal effect of this product on Enterococcus faecalis at sub-inhibitory concentrations. 9. Since the absorption of this product in the gastrointestinal tract is not affected by food, it can be taken on an empty stomach or after a meal, and can be taken with milk and other foods; taking it with food can reduce gastrointestinal reactions.

Keep away from light and store in sealed container.

187.5 mg (C16H19N3O5S125 mg and C8H9NO562.5 mg)

24 months

SANTA(Zhangjiakou)PHARMACEUTICAL Co., Ltd.

• Founded in:

  2002-08-15

• Address:

  No. 6, Tengfei Road, Dongshan High-tech Industrial Development Zone, Zhangjiakou, Hebei Province

• Tax NO.:

  91130700741518034N

• Registered Funds:

  9.93252 million yuan

• Website:

  Log in to view

• Email:

  Log in to view