Clindamycin phosphate vaginal gel

This drug is a chemical semi-synthetic clindamycin derivative. It has no antibacterial activity in vitro. It is rapidly hydrolyzed into clindamycin after entering the body and shows its pharmacological activity. Therefore, the antibacterial spectrum, antibacterial activity and therapeutic effect are the same as clindamycin, but its fat solubility and permeability are better than clindamycin. It can be taken orally, injected intramuscularly or intravenously. Compared with lincomycin, its antibacterial effect is 4-8 times stronger, it is well absorbed, has a high bone concentration, and has a good effect on anaerobic infections. This drug has strong antibacterial activity mainly against Gram-positive cocci and anaerobic bacteria, including Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus (except carbonyl Streptococcus), Streptococcus pneumoniae, Micrococcus among Gram-positive cocci, and Clostridium, Bacteroides, Fusobacterium, Propionibacterium, Eubacterium, and Necrotic Cocci among anaerobic bacteria.

Clindamycin phosphate

This product is a colorless, transparent semisolid gel.

Various infectious diseases caused by sensitive bacteria, such as tonsillitis, suppurative otitis media, sinusitis, empyema, lung abscess, skin and soft tissue infection, acute bronchitis, intra-abdominal infection, female pelvic and genital infection.

Patients with a history of allergy to clindamycin or lincomycin are contraindicated.

Adverse reactions of clindamycin phosphate vaginal preparations include: Urogenital system: dysfunction, vaginal pain, vaginal burning sensation, candidal vaginitis. Systemic effects: fungal infection. Adverse reactions with an incidence rate of less than 1%: Urogenital system: menstrual disorders, dysuria, etc. Systemic: abdominal cramps, abdominal pain, fever, abdominal pain, headache, etc. Digestive system: diarrhea, vomiting and nausea. (See the instructions inside the package for details)

This product has cross-resistance with lincomycin and clindamycin and is contraindicated in patients with a history of allergy to clindamycin or lincomycin.

Precautions for children: data is still lacking. Precautions for pregnancy and lactation: 1. Pregnant women should weigh the pros and cons before deciding whether to use this product. It is generally not suitable for use. 2. If lactating women use this product, they should stop breastfeeding. Precautions for the elderly: There are not enough clinical cases to prove whether there is a difference between the vaginal preparation of clindamycin phosphate over 65 years old and young people.

1. Clindamycin has a neuromuscular blocking effect and may enhance the effect of other neuromuscular blockers. Therefore, patients who use these drugs should use clindamycin with caution. 2. It has been confirmed that the antagonism between clindamycin and erythromycin and chloramphenicol is clinically significant, and the two drugs should not be used at the same time. 3. This product may be incompatible with neomycin, kanamycin, ampicillin, phenytoin sodium, barbiturate hydrochloride, aminophylline, calcium gluconate and magnesium sulfate. 4. This product may aggravate the depression of the respiratory center when used in combination with opioid analgesics.

Keep in a dark place and sealed. (Validity period) tentatively 2 years.

5g:0.1g (calculated as C18H33ClN2O5S)

18 months

Duoduo Pharmaceutical Co., Ltd.

• Founded in:

  1999-12-15

• Address:

  No. 555, Anqing Street, Dongfeng District, Jiamusi City, Heilongjiang Province

• Tax NO.:

  91230800716614788A

• Registered Funds:

  23.3425 million yuan

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