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Niuhuang Antihypertensive Capsule

Function and Efficacy

1. Blood pressure reduction: 0.4g crude drug/kg of Niuhuang Jiangya Capsule extract powder was administered for 4 weeks, which had a significant effect on reducing blood pressure, angiotensin II, aldosterone and endocrine hormone in spontaneously hypertensive rats (SHR), and there was a significant difference compared with the model group (P). Hypertension model, oral administration for three weeks, had a significant effect on reducing plasma renin activity (PRA), angiotensin II (AII) content and other indicators, and there was a significant difference compared with the model group (P. The results showed that Niuhuang Jiangya Capsule could significantly increase cardiac output and stroke volume, increase coronary blood flow, dilate coronary vessels, increase coronary sinus blood oxygen content, reduce myocardial oxygen consumption, and improve myocardial blood and oxygen supply; at the same time, it dilated peripheral blood vessels, decreased peripheral resistance, Adjust the compliance of myocardial blood vessels, and play a role in adjusting and improving the cardiovascular system. 3. Diuresis: The water load method was used to observe the diuretic effect of Niuhuang Jiangya Capsule. The test results showed that compared with the control group, Niuhuang Jiangya Capsule had a significant effect on increasing urine output and Na excretion. 4. Immunomodulation: It has a significant enhancement effect on the phagocytosis of rat peritoneal macrophages, indicating that it has a promoting effect on the activation and phagocytic function of macrophages and can improve immune function. 5. Anti-inflammatory: It has a significant inhibitory effect on xylene-induced ear inflammation in mice, with a rate of 42.2%, and has an antipyretic effect on P fever rabbits. 7. Sedation: The test intraperitoneal injection of sodium pentobarbital was conducted to observe the effect of Niuhuang Jiangya Capsule on the sleep time of mice. The results confirmed that Niuhuang Jiangya Capsule can significantly prolong the sleep time of mice.

Ingredients

Antelope horn, pearl, buffalo horn concentrated powder, artificial bezoar, borneol, white peony root, codonopsis pilosula and other flavors

Name Description Content CAS NO. Manufacturer
Atificial Cow-bezoarIngredients

Lowers blood pressure; increases cardiac output and stroke volume; improves myocardial blood and oxygen supply; anti-inflammatory; antipyretic; sedative

More
1002-00-2 2
BorneolIngredients

1. Blood pressure reduction: 0.4g crude drug/kg of Niuhuang Jiangya Capsule extract powder was administered for 4 weeks, which had a significant effect on reducing blood pressure, angiotensin II, aldosterone and endocrine hormone in spontaneously hypertensive rats (SHR), and there was a significant difference compared with the model group (P). Hypertension model, oral administration for three weeks, had a significant effect on reducing plasma renin activity (PRA), angiotensin II (AII) content and other indicators, and there was a significant difference compared with the model group (P. The results showed that Niuhuang Jiangya Capsule could significantly increase cardiac output and stroke volume, increase coronary blood flow, dilate coronary vessels, increase coronary sinus blood oxygen content, reduce myocardial oxygen consumption, and improve myocardial blood and oxygen supply; at the same time, it dilated peripheral blood vessels, decreased peripheral resistance, Adjust the compliance of myocardial blood vessels, and play a role in adjusting and improving the cardiovascular system. 3. Diuresis: The water load method was used to observe the diuretic effect of Niuhuang Jiangya Capsule. The test results showed that compared with the control group, Niuhuang Jiangya Capsule had a significant effect on increasing urine output and Na excretion. 4. Immunomodulation: It has a significant enhancement effect on the phagocytosis of rat peritoneal macrophages, indicating that it has a promoting effect on the activation and phagocytic function of macrophages and can improve immune function. 5. Anti-inflammatory: It has a significant inhibitory effect on xylene-induced ear inflammation in mice, with a rate of 42.2%, and has an antipyretic effect on P fever rabbits. 7. Sedation: The test intraperitoneal injection of sodium pentobarbital was conducted to observe the effect of Niuhuang Jiangya Capsule on the sleep time of mice. The results confirmed that Niuhuang Jiangya Capsule can significantly prolong the sleep time of mice.

More
507-70-0 1

Appearance

This product is a capsule, the contents of which are dark yellow powder; it has a slight fragrance, a slightly sweet and bitter taste, and a cooling sensation.

Usage and Dosage

Oral. 2-4 capsules at a time, once a day

Adverse Reactions

Not yet clear.

Precautions

Not yet clear

Drug Interactions

Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.

Storage

Containment

Packaging Specification

0.4g per tablet

Validity Period

36 months

Manufacturer

Hebei Tangwei Pharmaceutical Co., Ltd.

  • Founded in:

    2004-03-23
  • Address:

    No. 9, Jinguang Street, Cangzhou Development Zone
  • Tax NO.:

    91130901760301877Q
  • Registered Funds:

    30 million yuan
  • Email:

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