Fluticasone Propionate Cream

Fluticasone propionate is a highly effective glucocorticoid with local anti-inflammatory effects. After transdermal administration, the inhibitory effect on the HPA axis is very weak, so its therapeutic index is higher than most commonly used steroid preparations. Subcutaneous injection produces a strong systemic glucocorticoid effect, but the oral effect is weak, which may be due to metabolic inactivation. In vitro tests have shown that this drug has a strong affinity and agonist effect on the human glucocorticoid receptor. Fluticasone propionate has no expected pheromone effect and has no obvious effect on the central nervous system, peripheral nervous system, gastrointestinal tract, cardiovascular system, and respiratory system.

The main ingredient of this product is fluticasone propionate; its chemical name is: (6alpha;,11beta;,16alpha;,17alpha;)-6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-androsta-1,4-diene-17-carboxylic acid thioate, S-fluoromethyl ester;

This product is a white ointment with an emulsion base.

Adults: Suitable for various inflammatory and itchy skin diseases that can be relieved by corticosteroids, such as eczema, including specific <aclass=bluetarget=_blankhref=http://zzk.39.net/

Eczema/Dermatitis Adults and children over one year old (inclusive), apply a thin layer of cream to the affected area once a day. Other indications Apply a thin layer of cream to the affected area twice a day. Duration of use This product should be used daily until the symptoms of the disease are controlled. The frequency of medication should be controlled at the lowest effective dose. When children use this product, if the symptoms do not improve after 7-14 days of treatment, the drug should be discontinued and re-evaluated. If the symptoms are controlled (usually within 7-14 days), the frequency of medication should be reduced to the minimum effective dose and the shortest medication time. It is recommended to use this product continuously for no longer than 4 weeks. This product is for topical use.

Fluticasone propionate has good tolerance. In placebo-controlled clinical trials, the most common side effects are: skin infection, infectious eczema, viral warts, herpes simplex, impetigo, atopic dermatitis, eczema, eczema exacerbation, erythema, burning sensation, stinging, skin irritation, folliculitis, blisters, finger numbness and dry skin. In open clinical trials conducted in children, common side effects are: burning sensation, dark erythema, erythematous rash, facial telangiectasia, non-facial telangiectasia, and urticaria. If allergic reactions occur, the drug should be discontinued immediately. Adverse reactions such as inflammation, folliculitis, acne-like rash, hypopigmentation, perioral dermatitis, allergic contact dermatitis, secondary infection, skin atrophy, striae and prickly heat are rare, but their frequency increases significantly when occlusive therapy is used. Long-term and large-scale use of corticosteroids can cause local skin atrophy, manifested as thinning of the skin, the appearance of atrophic striae, telangiectasia, hypertrichosis and hypopigmentation. Long-term, large-scale or large-area application of corticosteroids can cause hyperfunction of the adrenal cortex through sufficient systemic absorption. This phenomenon is more common in infants and patients who are treated with occlusive therapy. The use of diapers by infants after applying the drug should also be considered as occlusive therapy. It is rare for pustular psoriasis to be induced during or after the use of corticosteroids to treat psoriasis. There have been reports of worsening symptoms and signs of skin diseases after medication.

1. Do not use this product if you are allergic to any of the ingredients in this product. 2. Do not use this product for rosacea, acne vulgaris, rosacea, perioral dermatitis, and primary skin viral infections (such as herpes simplex and chickenpox). 3. Do not use this product for perianal and vulvar pruritus. 4. Do not use this product for primary skin infections caused by fungi or bacteria. 5. Do not use this product for skin diseases in infants under 1 year old, including dermatitis and diaper rash.

Children's precautions: Contraindicated for use in infants under 1 year old with skin diseases, including dermatitis and diaper rash.

Not yet clear.

Store below 30°C.